Ataxia can be classified according to the onset into episodic, acute, intermittent and chronic ataxia. Acute ataxia in children is caused by CNS tumors, trauma, CNS infection, toxins, metabolic causes or stroke. Recurrent ataxia can be due to metabolic causes, seizures, basilar artery migraine or toxins. Chronic ataxia is usually the result of hereditary ataxia, CNS tumors, congenital anomalies...

Ataxia can be classified according to the onset into episodic, acute, intermittent and chronic ataxia. Acute ataxia in children is caused by CNS tumors, trauma, CNS infection, toxins, metabolic causes or stroke. Recurrent ataxia can be due to metabolic causes, seizures, basilar artery migraine or toxins. Chronic ataxia is usually the result of hereditary ataxia, CNS tumors, congenital anomalies...

An unusual presentation is reported of salmonellosis, frank haematuria and chronic septicaemia arising during an outbreak of food poisoning caused by Salmonella eimsbuettel. The patient whose gut was colonized gave a history of chronic pyrexia and weight loss and suffered an intermittent urinary infection but had no gastroenteritis.

Chronic-intermittent hypoxia (CIH) was postulated to activate thalamic regions that are synaptically related to autonomic-related areas of the cerebral cortex. Animals exposed to CIH for 30 days exhibited c-fos labeling in paraventricular thalamic and lateral habenular nuclei. Our findings strongly suggest activation of a diencephalic network that participates in behavioral responses to chronic...

PURPOSE Controlled-release formulations of Valproate (VPA) reduce side effects by minimizing peak plasma VPA concentrations in patients with epilepsy. However, the impact of this on anti-seizure efficacy has not been thoroughly explored. Here the pharmacokinetics and pharmacodynamics of chronic intermittent (consequently, peak VPA concentrations) and continuous VPA administration were directly ...

Spontaneous thrombosis of abdominal aortic aneurysm (AAA) is an uncommon condition. Chronic thrombosed AAA are related to occlusive iliac disease and often present with intermittent claudication. However, the symptoms related to expansion of the aneurysm and risk of rupture must be considerable, even in thrombosed aorta. We present our experience with three consecutive cases of chronic thrombos...

Asthma is a chronic inflammatory disease of the airways. Symptoms of asthma are variable. That means that they can be mild to severe, intermittent to chronic. The one point to remember is that even when symptoms are mild, asthma should not be ignored. Untreated or under treated, asthma can lead to severe respiratory distress and in rare cases, sudden death. Asthma is the most common chronic dis...

Chronic constant hypoxia (CCH) and chronic intermittent hypoxia (CIH) are known to have deleterious effects on the central nervous system. Because of the difference in the pattern of hypoxic exposure, it is possible that the pathological outcome would vary. The N-acetyl aspartate/creatine (NAA/Cr) ratio is a reliable marker of neuronal integrity, and this can be noninvasively measured by proton...

Objectives: Elexacaftor/Tezacaftor/Ivacaftor (ETI) improves outcome in patients with cystic fibrosis. To evaluate possible effects of ETI specifically on Pseudomonas aeruginosa (PA) we assessed sputum cultures and PA antibodies people CF (PwCF). Methods: At the Centre Innsbruck, PwCF had routine evaluation serum analysis before during ETI. Induced was collected in-house physiotherapy. Results f...

crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...