A dog presented with cutaneous nodules, enlarged lymph nodes and oedema in limbs, face and abdomen. The diagnosis of visceral leishmaniasis was established by identification of Leishmania amastigotes within macrophages from skin and popliteal lymph node biopsies. At necropsy, lesions were found in different organs, but it was particularly striking to observe large areas of pallor in the myocard...

ABSTRACT: American cutaneous leishmaniasis is considered endemic in 18 countries the Americas, including Brazil, and part of group neglected infectious diseases. In state Alagoas, from 2008 to 2018, 676 cases were reported SINAN. Therefore, objective was describe epidemiological sociodemographic characteristics treated for leishmaniasis, during years 2018. This a descriptive, ecological, cross-...

Leishmaniasis are notifiable diseases, characterized by severe clinical manifestations, being caused obligate intracellular protozoa, belonging to the genus Leishmania, where species L. (L.) infantum and (V.) braziliensis responsible for most cases. of leishmaniasis in Brazil. Many studies indicate need investigations into exact role animal epidemiology leishmaniasis, particularly skunks rodent...

Cutaneous leishmaniasis has been endemic in Aleppo, Syria, for generations. Recently there has been a clear increase in the incidence of the disease, and more patients have shown a lack of response to antimonials. We report the results of a survey, undertaken over the period 2-17 January 1995, at a general hospital in Aleppo, of all patients presenting with cutaneous leishmaniasis. Patients wer...

● Canine visceral leishmaniasis is a severe systemic disease caused by the diphasic protozoan parasite Leishmania infantum in the Old World and L. chagasi in the New World. ● The geographical distribution of the disease is dependent on its insect vector, the sandfly Phlebotomus spp. in the Old World and Lutzomyia spp. in the New World. ● Common clinical signs are skin lesions, weight loss, anor...

Infection is the outcome of a contest between a pathogen and its host. In the disease leishmaniasis, the causative protozoan parasites are harbored inside the macrophages. Leishmania species adapt strategies to make the infection chronic, keeping a balance between their own and the host's defense so as to establish an environment that is favorable for survival and propagation. Activation of per...

Kala-azar (visceral leishmaniasis) is endemic in southern Iran. We retrospectively evaluated 367 infants and children with visceral leishmaniasis at hospitals affiliated to Shiraz University of Medical Sciences in Fars Province (located in the southwestern part of Iran). Seasonal variation was observed with more cases presenting in late winter, spring and a few in summer. The predominant clinic...

BACKGROUND Co-infection of leishmaniasis and HIV is increasingly reported. The clinical presentation of leishmaniasis is determined by the host immune response to the parasite; as a consequence, this presentation will be influenced by HIV-induced immunosuppression. As leishmaniasis commonly affects the skin, increasing immunosuppression changes the clinical presentation, such as in post-kala-az...

Immunological data show that type 2 diabetes (T2D) manifests autoimmune features. We wanted to test the association epidemiologically by assessing subsequent diagnosis of T2D following diagnosis of autoimmune disease (AId) and subsequent AId after T2D in the same individuals. Patients were identified from three Swedish health databases. A total of 32 different AId were included. Standardized in...

The term leishmaniasis comprises a group of diseases caused by different species of a protozoon called Leishmania. Leishmaniasis is found worldwide, and is considered to be endemic in 88 countries. There are three main clinical forms of leishmaniasis: visceral leishmaniasis, cutaneous leishmaniasis and mucocutaneous leishmaniasis. Exclusive involvement of the mucosa is very rare. We present a s...