Abbreviations: chronic obstructive pulmonary disease, COPD; quality adjusted life years, QALYs; forced expiratory volume in 1 second, FEV1; forced vital capacity, FVC Citation: Pinnock H, Sohanpal R. Editorial-Chronic obstructive pulmonary disease: reduced nihilism, but there is still a ways to go. Chronic Obstr Pulm Dis (Miami). 2016; 3(3): 605-609. doi: http://dx.doi.org/10.15326/jcopdf.3.3.2...

BACKGROUND The World Health Organization has estimated that by 2030, chronic obstructive pulmonary disease will be the third leading cause of death worldwide. Most knowledge of chronic obstructive pulmonary disease is based on studies performed in Europe or North America and little is known about the prevalence, patient characteristics and change in lung function over time in patients in develo...

BACKGROUND AND AIM The multi-drug resistant-1 (MDR-1) gene is located on human chromosome 7 and encodes a glycosylated membrane protein that is a member of the ATP-binding cassette transporters superfamily. The aim of the study was to reveal the role of the C3435T MDR-1 gene polymorphism in chronic obstructive pulmonary disease. METHOD DNA samples from 41 patients with chronic obstructive pul...

Tiotropium represents a new generation of inhaled therapy. No other inhaled product has demonstrated effectiveness with once-daily dosing. Treatment has been associated with improved lung function, decrease in the number of exacerbations, increase in the time to first exacerbation, and improved quality of life. Adverse effects appear to be mild in nature, and the only significant adverse effect...

1. Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H. Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003; 22: 912–919. 2. Szafranski W, Cukier A, Ramirez A, et al. Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur Respir J 2003; 21: 74–81. 3. Calverley P, Pauwel...

The six-minute walk test (6MWT) is a well-tolerated test which reflects daily activities and can be easily used in clinical practice. The 6MWT provides information about functional capacity, response to therapy and prognosis across a range of chronic cardiopulmonary conditions. Moreover, the 6MWT is sensitive to the common therapies used for chronic obstructive pulmonary disease, such as pulmon...

Background: The burden of chronic obstructive pulmonary disease to patients, their caretakers, and health system is gradually increasing associated with the morbidity, mortality, disability adjusted life years higher costs. Self-management COPD a vital strategy for its management. This study aims develop, implement, evaluate an informatics platform home-based self-management Chronic Obstructive...