There is the need to integrate existing toxicity data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would also reduce time and cost-consuming aspects of these tests and reduce animal usage. In this work, based on data extracted from literature, we have assessed the advantages that a dynamic biology-toxicant fate co...

Organophosphate chronic toxicity has been evaluated in this study. Biological screening for organophosphate insecticide-exposed workers is mostly recommended for mixers, loaders, formulators and spraymen. We have studied 17 occupationally exposed persons to pesticides. Using Ellman's colorimetric method, their plasma cholinesterase activities have been measured. Results show that the appear...

Background: Fish have been at high risk of atrazine toxicity. Comparative atrazine toxicity on the tissues of Clarias gariepinus is scanty. Therefore, acute and chronic effects of atrazine on some biochemical parameters in Clarias gariepinus were investigated in this study. Methods: Atrazine toxicity was determined by assessing the responses of glucose, protein, alanine aminotransferase (ALT...

recently, some natural products have been used in the fields as alternative to synthetic compounds, to minimize the negative impacts to the environment. this study aimed to verify the effects of neem-based bio-pesticide in causing acute toxicity for a fish and chronic toxicity for a microcrustacean. to this end, danio rerio and daphnia magna were exposed to various concentrations of a neem-base...

background: fish have been at high risk of atrazine toxicity. comparative atrazine toxicity on the tissues of clarias gariepinus is scanty. therefore, acute and chronic effects of atrazine on some biochemical parameters in clarias gariepinus were investigated in this study. methods: atrazine toxicity was determined by assessing the responses of glucose, protein, alanine aminotransferase (alt), ...

Nanosilver has recently been recognized as an antimicrobial agent. Although this nanoparticlecan be used in medical applications but its dermal and systemic toxicity via dermal exposure hasnot been completely determined yet. The aim in this study was to investigate the potential dermaltoxicity of Nanosilver in subchronic method. Before the colloidal silver nanoparticle toxicityevaluation, their...

Background: Trachyspermum ammi is one of the prominent plant in traditional medicine of the east with several medicinal effects such as improvement of stomach disease, digestive disorder, diarrhea, hemorrhoid, bladder stones, respiratory disease and etc. Medicinal plants is one of the important reason of toxicity particularly in children and the elderly therefore, evaluation of the toxic effect...