BACKGROUND Predicted maturity offset and age at peak height velocity are increasingly used with youth athletes, although validation studies of the equations indicated major limitations. The equations have since been modified and simplified. OBJECTIVE The objective of this study was to validate the new maturity offset prediction equations in independent longitudinal samples of boys and girls. ...

Received: 19 Mar 2014 Accepted: 9 Oct 2014 Abstract Background and Aim: To estimate the age in forensic identification, when none of the other identification methods are feasible, the teeth are used. The aim of the present study was to estimate the age from pulp/tooth area ratio (AR) by digital panoramic radiography in patients referred to a radiology clinic. Materials and Methods: In this diag...

DNA methylation (DNAm) is a key mechanism for regulating gene expression in animals and levels are known to change with age. Recent studies have used DNAm changes as a biomarker to estimate chronological age in humans and these techniques are now also being applied to domestic and wild animals. Animal age is widely used to track ongoing changes in ecosystems, however chronological age informati...

Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood. Here we perform a whole-blood gene expression meta-analysis in 14,983 individuals of European ancestry (including replication) and identify 1,497 genes that are differentially expressed with chronological age. The age-associated genes do...

Multi-modal MRI data analysis can be used to predict a child or young adult's age. Most, but not all, individuals' brain-derived age estimate is close to their chronological age.

OBJECTIVE To investigate the differences between skeletal and chronological age and to assess the role of maturity status, anthropometric data, and football related variables in explaining injury statistics in elite schoolboy footballers. DESIGN Prospective study of injuries in schoolboy footballers according to skeletal age. SETTING Premier league football club in England. PARTICIPANTS 2...

BACKGROUND The ability to correctly assess the patient's bone age is an important element that allows correct diagnosis and proper planning of the start of orthodontic treatment. OBJECTIVE The objective of this study was to estimate bone age in children with congenital craniofacial defects - primary and secondary palate cleft. MATERIAL AND METHODS The analysis covered lateral head images of...

Introduction: Age estimation is one of the important issues for treatment planning and determination of patient’s rights in forensic medicine. In spite of various methods which have been introduced for age estimation, there is still no specific practical, non-invasive, and rapid method of age estimation for Iranian population. The aim of this study was to find a precise criteria for age estimat...

As an important post-translation modifying process, glycosylation significantly affects the structure and function of immunoglobulin G (IgG) molecules and is essential in many steps of the inflammatory cascade. Studies have demonstrated the potential of using glycosylation features of IgG as a component of predictive biomarkers for chronological age in several European populations, whereas no s...

Indexes for arterial stiffness are, by their nature, influenced by the ambient blood pressure due to the curvilinear nature of arterial compliance. We developed a new concept of the "Modelflow aortic age," which is, theoretically, not influenced by the ambient blood pressure and provides an easily understood context (biological vs. chronological age) for measures of arterial stiffness. The purp...