نتایج جستجو برای: cigarette smoke

تعداد نتایج: 86370  

Journal: :American journal of respiratory and critical care medicine 2011
Kelly S Schweitzer Brian H Johnstone Jana Garrison Natalia I Rush Scott Cooper Dmitry O Traktuev Dongni Feng Jeremy J Adamowicz Mary Van Demark Amanda J Fisher Krzysztof Kamocki Mary Beth Brown Robert G Presson Hal E Broxmeyer Keith L March Irina Petrache

RATIONALE Adipose-derived stem cells express multiple growth factors that inhibit endothelial cell apoptosis, and demonstrate substantial pulmonary trapping after intravascular delivery. OBJECTIVES We hypothesized that adipose stem cells would ameliorate chronic lung injury associated with endothelial cell apoptosis, such as that occurring in emphysema. METHODS Therapeutic effects of system...

Journal: :The American journal of physiology 1999
A Felix Ofulue Mary Ko

The aim of this study was to ascertain the putative roles of neutrophils or macrophages in the pathogenesis of cigarette smoking-induced emphysema on the basis of effects of anti-neutrophil (anti-PMN) antibody or anti-monocyte/macrophage (anti-MoMac) antibody on the development of emphysema in cigarette smoke-exposed rats. Rats were treated with rabbit anti-PMN or anti-MoMac antibody and expose...

Journal: :iranian journal of pharmaceutical sciences 0
parvaneh naserzadeh faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. jalal pourahmad faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

cigarette smoking is one of the main risk factors for premature human death associated to a variety of respiratory and vascular diseases, and cancer due to containing hundreds of toxicants. rat mitochondria were obtained by differential ultracentrifugation and incubated with different concentrations (1, 10 and 100%) of standardized cigarette smoke extract (cse). our results showed that cigarett...

Journal: :Gut 2000
L Ma W P Wang J Y Chow S K Lam C H Cho

BACKGROUND Cigarette smoking was shown to delay gastric ulcer healing and reduce synthesis of mucus, which is important for gastric ulcer protection and healing. Polyamines are important in these processes. AIMS To study the effects of cigarette smoking on the synthesis of mucus and to investigate if such an effect is acting by interference with the polyamine pathway. METHODS Gastric mucosa...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2006
Carolyn J Baglole Seth M Bushinsky Tatiana M Garcia Aruna Kode Irfan Rahman Patricia J Sime Richard P Phipps

Cigarette smoke is the principal cause of emphysema. Recent attention has focused on the loss of alveolar fibroblasts in the development of emphysema. Fibroblasts may become damaged by oxidative stress and undergo apoptosis as a result of cigarette smoke exposure. Not all smokers develop lung diseases associated with tobacco smoke, a fact that may reflect individual variation among human fibrob...

Journal: :Journal of dental research 1983
R Yu A Koran C N Raptis R G Craig

In this study, a maxillofacial silicone elastomer was stained with cigarette smoke. The stain was then removed by solvent extraction using 1,1,1-trichloroethane. The cigarette smoke produced large color changes in the elastomer as measured from spectrophotometric reflectance curves. The solvent was totally effective in removing the cigarette stain without changing the color of the silicone base.

2017
Mozhgan Firouzbakht Karimallah Hajian-Tilaki Maryam Nikpour Zahra Banihosseini

BACKGROUND Exposure of lactating women to environmental cigarette smoke may increase cotinine in breast milk, which in turn may reduce the volume of milk and the duration of breastfeeding. OBJECTIVES To assess the relationship between exposure to environmental cigarette smoke and breastfeeding behavior. MATERIALS AND METHODS This prospective cohort study was conducted on 290 mothers in Babo...

Journal: :Thorax 1987
G Woodman S P Newman D Pavia S W Clarke

Ten symptomless smokers were switched from their usual cigarette to a low tar, low nicotine test cigarette for two weeks to investigate their immediate response and subsequent acclimatisation to the test cigarette. The tar (T) and nicotine (N) yields of the test cigarettes were T = 3.8 mg, N = 0.6 mg; the median yields of the usual cigarettes were T = 16.4 mg, N = 1.4 mg. The subjects were moni...

Journal: :The Journal of toxicological sciences 2006
Yasuo Fukano Masako Oishi Fumika Chibana Satoshi Numazawa Takemi Yoshida

Airway epithelium is exposed to inhaled exogenous sources. Injury of the alveolar epithelium by cigarette smoking is presumed to be an important process in the pathogenesis of smoking-related pulmonary diseases. Current mechanistic assays that measure the toxicity of cigarette smoke focus on carcinogenesis. However, there is a need to design assays relevant to other disease processes. Oxidative...

Journal: :The European respiratory journal 2012
A C Toledo R M Magalhaes D C Hizume R P Vieira P J C Biselli H T Moriya T Mauad F D T Q S Lopes M A Martins

It has recently been suggested that regular exercise reduces lung function decline and risk of chronic obstructive pulmonary disease (COPD) among active smokers; however, the mechanisms involved in this effect remain poorly understood. The present study evaluated the effects of regular exercise training in an experimental mouse model of chronic cigarette smoke exposure. Male C57BL/6 mice were d...

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