Calf-brain coated vesicles were incubated with ATP and a cytosol fraction. As much as 90% of the clathrin was selectively released within 10 min at 37 degrees C without detectable proteolysis. This uncoating process required the presence of both ATP and cytosol. Empty cages of clathrin could also be dissociated in a similar manner. A nonhydrolyzable analogue, 5'-adenylylimidodiphosphate (AMP-PN...

CASE REPORT We report a case of Coats' disease in a 10-year-old-girl who presented with a profound visual deficit, exudative retinal detachment, vascular telangiectasias and subretinal lipid, who underwent treatment with an intravitreal injection of bevacizumab (AVASTIN(TM)). Serial examinations documented an involutional response with a reduction of the subretinal fluid, exudates and macular t...

In the present study, a new copolymer containing pyrazole substituted 1,3-diphenyl-1H-pyrazol-5-yl methacrylate (DPMA) and styrene (St) units, [poly(DPMA-co-St)], was synthesized. Thermal degradation kinetics of system investigated in detail with thermogravimetric analysis (TGA) technique. An increase thermal stability from 252.02 °C to 274.89 observed depending on change heating rate (5 °C/min...

"Here they are, boys; get your tools ready." ... As they ran, they pulled weapons from under their coats, hatchets, knuckle-dusters, hammers, and bars of iron.