نتایج جستجو برای: clinical trial

تعداد نتایج: 1365604  

Journal: :Annals of statistics 2009
Rui Song Michael R Kosorok Jason P Fine

We consider tests of hypotheses when the parameters are not identifiable under the null in semiparametric models, where regularity conditions for profile likelihood theory fail. Exponential average tests based on integrated profile likelihood are constructed and shown to be asymptotically optimal under a weighted average power criterion with respect to a prior on the nonidentifiable aspect of t...

Journal: :Occupational health & safety 2011
Ray Morris

Productivity often hinges on workers' ability to perform their jobs without worrying about injury. An internal assessment can help companies determine the reason for injuries that slow employees, stall processes, and result in escalating medical and indemnity costs. Implementing recommended changes and training employees to encourage their acceptance and use of new equipment can go a long way i...

Journal: :Lifetime data analysis 2012
Chunjie Wang Jianguo Sun Liuquan Sun Jie Zhou Dehui Wang

This paper discusses nonparametric estimation of a survival function when one observes only current status data (McKeown and Jewell, Lifetime Data Anal 16:215-230, 2010; Sun, The statistical analysis of interval-censored failure time data, 2006; Sun and Sun, Can J Stat 33:85-96, 2005). In this case, each subject is observed only once and the failure time of interest is observed to be either sma...

Journal: :Lifetime data analysis 2001
S Murray A A Tsiatis

Murray and Tsiatis (1996) described a weighted survival estimate that incorporates prognostic time-dependent covariate information to increase the efficiency of estimation. We propose a test statistic based on the statistic of Pepe and Fleming (1989, 1991) that incorporates these weighted survival estimates. As in Pepe and Fleming, the test is an integrated weighted difference of two estimated ...

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