Sepsis-induced myocardial injury is a detrimental disorder for intensive care medicine due to its high rates of morbidity and mortality. Data suggest that nuclear factor (NF)-κB serves a critical role in the pathogenesis of myocardial injury. Hydrogen sulfide (H2S) serves an important role in the physiology and pathophysiology of regulatory mechanisms, particularly during an inflammatory reacti...

It is suspected that environmental exposure to non-syndromic oral clefts, which includes cleft lip (CL), and palate (CLP) has an effect on epigenetic mechanisms, particularly deoxyribonucleic acid (DNA) methylation. DNA methylation will be expressed during facial morphogenesis have impact development. This study aimed observe differences in between CL CLP, mothers CLP mothers, correlation mothe...

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection with a high mortality. 5-Hydroxytryptamine (5-HT) is an important regulatory factor in inflammation. The aim of this study is to investigate the role of 5-HT on cecal ligation and puncture- (CLP-) induced sepsis in the mouse model. CLP was performed on C57B/6 wild-type (WT) mice and try...

Kidney injury, heart injury, and cytokine-induced vascular hyperpermeability are associated with high rates of morbidity and mortality in sepsis. Although the mechanism remains unknown, apolipoprotein A-I (apoA-I) mimetic peptide 4F reduces inflammation and protects HDL levels, which are reduced in sepsis. We hypothesized that 4F also protects kidneys and hearts in a rat model of cecal ligation...

BACKGROUND Immunonutrition in sepsis, including n-3 poly-unsaturated fatty acids (PUFAs) or L-arginine supplementation, is a controversial issue that has yielded a great number of studies for the last thirty-five years, and the conclusions regarding the quantity and quality of this support in patients are deceiving. The aim of the present experimental study is to investigate the effects of a pr...

Constraint logic programming is one of the most attractive research areas in logic programming. Due to [JL87] the theoretical foundation of a general constraint logic programming language scheme CLP(X ) is available. Unfortunately, implementing a CLP(X ) system for some domain X is a difficult task. The problematic points are providing a constraint solver and ensuring the incrementality of the ...

A widely used property of Prolog is that it is possible to write Prolog programs to construct and manipulate other Prolog programs in a very general manner. Unfortunately , this property is not carried over to richer languages such as CLP(R) { the manipulation of CLP(R) programs in CLP(R) is quite limited. The reason is that the equality of terms in CLP(R) is not based on their syntactic struct...