BACKGROUND Umbilical cord blood (UCB) is believed to be a highly valuable source of hematopoietic stem cells for transplantation. Objective: To investigate the prevalence of active and latent human cytomegalovirus (CMV) infection in UCB donors in Iranian population. METHODS A total of 825 UCB samples was collected under standard procedures and analyzed for the presence of CMV DNAs in buffy co...

The objective of this research was to identify maternal and fetal characteristics as prognostic markers of congenital cytomegalovirus (CMV) infection. This is a descriptive study of 13 cases of congenital CMV infection referred to Institute de Puericulture et Perinatologie de Paris (IPP) from January 2005 to October 2006. Amniotic fluid puncture was performed to research CMV polimerase chain re...

BACKGROUND Measures to prevent transfusion-transmitted cytomegalovirus (TT-CMV) infection after hematopoietic stem cell transplantation (HSCT) include transfusion of CMV antibody-negative blood units and/or transfusion of leukoreduced cellular blood products. We assessed the incidence of TT-CMV in CMV-seronegative patients receiving CMV-seronegative HSC transplants, who were transfused with leu...

cytomegaloviurs (cmv) is the most frequent cause of congenital infection in humans. in various parts of the world the prevalence of antibodies to cmv ranges from 40-100%. the prevalence of primary infection with cmv in pregnant iranian women and risk of congenital cmv infection in their neonates are unknown. to determine the prevalence of cmv infection in primiparous pregnant (youner) women and...

Discussion Efalizumab is a recombinant humanized monoclonal antibody used for chronic plaque psoriasis refractory to other systemic treatments (methotrexate, ciclosporin, PUVA therapy). The most frequent efalizumab side effects are influenza syndrome, infections, pruritus and arthritis [1–4] . Malignancies are not increased in patients treated with efalizumab [5] . A study of the clinical trial...

abstract cytomegalovirus (cmv) is a virus that can be consider as invasive infection after transplantation or chemotherapy, long-term corticosteroid users or in immunodeficient patients such as hiv. different complications were seen in immunocompetent patients but colitis rarely occurs. the diagnosis of cmv was based on pathology by colonoscopy, positive cmv antigen and high cmv-igm titer serum...

Objective—To study the association between anti-ganglioside antibody responses and Guillan-Barré syndrome (GBS) after a recent cytomegalovirus (CMV) infection. Methods—Enzyme linked immunosorbant assay (ELISA) was undertaken on serum samples from 14 patients with GBS with recent cytomegalovirus (CMV) infection (CMV+GBS) and 12 without (CMVGBS), 17 patients with other neurological diseases (OND)...

introduction: cytomegalovirus (cytome-galovirus: cmv) infection is a common cause of morbidity and mortality in patients who are the candidate for liver transplant. serological monitoring of individuals rece-iving and giving the liver transplant is necessary for prevention, early diagnosis and treatment strategies and reducing the prevalence of infection. the aim of this study was to assess the...

OBJECTIVES To define the incidence of congenital cytomegalovirus (CMV) infection in a defined population in Israel as diagnosed by urine polymerase chain reaction (PCR), and to assess the utility of this method for screening for congenital CMV infection. DESIGN A convenient sample of urine specimens from asymptomatic newborns were subjected to CMV PCR. Positive results were validated by urine...