Calcineurin (CN), a calcium- and calmodulin-dependent protein phosphatase, plays a significant role in the central nervous system. Previously, we reported that forebrain-specific CN knockout mice (CN mutant mice) have impaired working memory. To further analyze the behavioral effects of CN deficiency, we subjected CN mutant mice to a comprehensive behavioral test battery. Mutant mice showed inc...

Let n > m 2:: 4 be positive integers. The edge framing number efr( Cm, Cn) of Cm and Cn is defined as the minimum size of a graph every edge of which belongs to an induced Cm and an induced Cn. We show that efr(Cm,Cn) = n+4 ifn = 2m-4 and m 2:: 5, efr(Cm,Cn) = n+5 if n = 2m-6 and m ~ 7 and efr(Cm1 Cn) = n+6 if n = 2m-8 (m ~ 10) or m = n -1 (where n ~ 5 and n ¢ {6,S}) or m = n 2 (n = 6 or n 2:: ...

Our cyanylation (CN)-based methodology for determining disulfide structure of cystinyl proteins overcomes the limitations of conventional proteolytic methods. However, the CN-based method has the potential drawback that occasionally some CN-induced cleavage fragments may not be detected. We show that CN-based methods can overcome the failure to detect fragments by demonstrating the existence of...

Dedicated to Professor Heinrich Nöth on the occasion of his 85th birthday Recrystallization of silver pentacyanocyclopentadienide Ag[C5(CN)5] from N,N-dimethylformamide (DMF) gives the polymeric 1 : 1 complex [Ag{C5(CN)5}(DMF)] (1). The Ag+ cation is coordinated by three N atoms of three different [C5(CN)5] anions and two O atoms of two DMF molecules. Each [C5(CN)5] is coordinated via three nei...

Using the computational approach introduced in [Agore A.L., Bontea C.G., Militaru G., J. Algebra Appl. 12 (2013), 1250227, 24 pages] we classify all coalgebra split extensions of H4 by k[Cn], where Cn is the cyclic group of order n and H4 is Sweedler’s 4-dimensional Hopf algebra. Equivalently, we classify all crossed products of Hopf algebras H4#k[Cn] by explicitly computing two classifying obj...

Slight changes in the coordination structure of the manganese(v)-nitrido anionic complex, [MnV(N)(CN)4]2-, induced by using a "lipid package" approach markedly made an impact on the corresponding redox potentials. The single crystals of four lipid assemblies, [dabco-(CH2)n-1-CH3]2[Mn(N)(CN)4(H2O)]·xH2O (n = 15, 16, 17 and 18; dabco = 1,4-diazabicyclo[2,2,2]octane), were synthesized and solid-st...

We synthesized an indolium–coumarin dyad (1) and its derivatives with –Cl (2), –N(CH3)2 (3), or –NO2 (4) substituent, and used them for fluorometric detection of cyanide anions (CN(-)) in aqueous media. All of the dyads exhibit fluorescence enhancement by CN(-) via a nucleophilic interaction of CN(-) with the indolium carbon atoms. Their fluorescence response and selectivity to CN(-), however, ...

A graphene/nitrogen-enriched sandwiched composite (HAT-CN/Gr) as readily obtained from in-situ combination of HAT-CN and GO through sonication thermal reduction. The resultant HAT-CN/Gr cathode exhibits excellent lithium storage performance.