The effects of chrysotile and benzo(a)pyrene (BaP) co-exposure on uptake, metabolism and BaP binding to nucleic acids were investigated in normal human fibroblasts. A significant enhancement in these parameters was found when co-exposure was carried out under serum-free conditions. In the presence of serum, only a slight enhancement of BaP uptake was detected, while metabolism and binding to nu...

Blood-Contacting Surfaces In article number 2102214, Jun Ki Hong, Anna Waterhouse, Chiara Neto, and co-workers report that tethered-liquid perfluorocarbons show low adhesion of blood components. The cover image is a scanning electron micrograph revealing minimal platelets after incubation in human whole blood. bumpy background the tethered-perfluorocarbon layer which stabilizes liquid perfluoro...

A microfluidic platform is presented which fully automates all incubation steps of a three-stage, multiplexed magnetic bead immunoassay, such as the Luminex® xMAP technology. Magnetic actuation is used to transfer the microbeads between co-infused adjacent laminar flow streams to transport the beads into and out of incubation and wash solutions, with extended incubation channels to allow suffic...

Background: Anthocyanins (ACNs) are the most prevalent flavonoids in berries and their health promoting effects on vascular functions are still discussed. The aim of the present study was to identify the antiinflammatory effect of ACNs on activated human umbilical vein endothelial cells (HUVECs) after their transport across an epithelial monolayer. Study design: We established a transwell epith...

Our recent studies suggest that human squamous cell carcinoma of the head and neck (SCCHN) is capable of activating an intrinsic mechanism of programmed-cell death in interacting lymphocytes in situ and in vitro. The current study used Jurkat T-cell line as a model to investigate intracellular apoptotic events in T cells interacting with SCCHN. Apoptosis induced in T lymphocytes by tumor cells ...

Egg storage beyond 7 d is associated with an increase in incubation duration and a decrease in hatchability and chick quality. Negative effects of prolonged egg storage may be caused by changes in the embryo, by changes in egg characteristics, or by both. An adjustment in storage air composition may reduce negative effects of prolonged egg storage because it may prevent changes in the embryo an...