This study was aimed at investigating the effects of Eucheuma cottonii (EC) in oxidative stress and the signaling for mucin synthesis in rat lungs chronically exposed to coal dust. Coal dust with concomitant oral administration of ethanolic extract of EC at doses of 150 (EC150) or 300 mg/kg BW (EC300) compared to exposed to PM10 coal dust at doses of 6.25 (CD6.25), 12.5 (CD12.5), or 25 mg/m(3) ...

objective(s):to investigate the effect of eucheuma cottonii on alveolar macrophages (am) and malondialdehyde (mda) levels in bronchoalveolar lavage fluids (balf) in particulate matter 10 (pm10) coal dust-exposed rats. materials and methods: ten groups, including a non exposed group and groups exposed to coal dust at doses of 6.25 (cd6.25), 12.5 (cd12.5), or 25 mg/m3 (cd25) an hour daily for 6 m...

BACKGROUND Coal workers' pneumoconiosis (CWP) is a preventable, but not fully curable occupational lung disease. More and more coal miners are likely to be at risk of developing CWP owing to an increase in coal production and utilization, especially in developing countries. Coal miners with different occupational categories and durations of dust exposure may be at different levels of risk for C...

Coal workers' pneumoconiosis, also known as "black lung disease," is an occupational lung disease caused by overexposure to respirable coal mine dust. Inhaled dust leads to inflammation and fibrosis in the lungs, and coal workers' pneumoconiosis can be a debilitating disease. The Federal Coal Mine Health and Safety Act of 1969 (Coal Act),* amended in 1977, established dust limits for U.S. coal ...

The potential of coal mine dust to cause disabling pneumoconiosis has long been recognised, but research now suggests that pneumoconiosis is not the only respiratory hazard of coal mining.Over the last 30 years evidence has accumulated that miners also experience an excess of chronic obstructive pulmonary disease (COPD), and this has led the British Government to classify chronic bronchitis and...

Dust concentration levels in underground coal mines are of primary importance and have to be controlled to prevent pulmonary disease in miners. Different mining areas are exposed to different dust levels and to minimize the probability of occupational respiratory disease of coal miners, it is necessary to evaluate dust concentration in the different working areas. This study aimed to evaluate d...

Objective(s):To investigate the effect of Eucheuma cottonii on alveolar macrophages (AM) and malondialdehyde (MDA) levels in bronchoalveolar lavage fluids (BALF) in particulate matter 10 (PM10) coal dust-exposed rats. Materials and Methods: Ten groups, including a non exposed group and groups exposed to coal dust at doses of 6.25 (CD6.25), 12.5 (CD12.5), or 25 mg/m3 (CD25) an hour daily for 6 ...

The potential of coal mine dust to cause disabling pneumoconiosis has long been recognised, but research now suggests that pneumoconiosis is not the only respiratory hazard of coal mining.Over the last 30 years evidence has accumulated that miners also experience an excess of chronic obstructive pulmonary disease (COPD), and this has led the British Government to classify chronic bronchitis and...

Bergman, I., and Casswell, C. (1972). Brit. J. industr. Med., 29, 160-168. Lung dust and lung iron contents of coal workers in different coalfields in Great Britain. Lung dust analyses from seven coalfields are studied and it is found that the average dust composition varies significantly with the rank of coal. The higher the rank, the higher the coal percentage and the lower the quartz percent...

BACKGROUND The mortality experience over 22-24 years of 8,899 working coal miners initially medically examined in 1969-1971 at 31 U.S. coal mines was evaluated. METHODS A cohort life-table analysis was undertaken on underlying causes of death, and proportional hazards models were fitted to both underlying, and underlying and contributing causes of death. RESULTS Elevated mortality from nonv...