An immunological study of B cells in patients with colitis that was associated with Hirschsprung's disease was undertaken and compared with that in patients with ulcerative colitis and in normal controls. There was an appreciable increase in IgA and a decrease in IgG in both disease groups. Humoral reaction in colitis associated with Hirschsprung's disease seems to be indistinguishable from tha...

The relationship of pyoderma gangrenosum and ulcerative colitis remains uncertain. We investigating 14 patients with pyoderma gangrenosum by colonoscopy with multiple biopsies. Six patients had ulcerative colitis and all of these had disease affecting the whole colon. There were no correlations between exacerbations of the colitis and the onset or course of pyoderma gangrenosum. The remaining e...

1. Professor of Medicine, Gastroenterology Unit, Universidad Nacional de Colombia, Gastroenterologist at the Clínica Fundadores, Clínica Carlos Lleras Restrepo, Hospital Fundación San Carlos 2. Internal Medicine Clínica Fundadores 3. Professor of Medicine, Gastroenterology Unit, Universidad Nacional de Colombia, Gastroenterologist, Hospital El Tunal ........................................ Rece...

BACKGROUND Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS The aim of the present study was to evaluate bone density and metabolism in patients with microscopic colitis. METHODS Fourteen patients microscopic colitis...

THE CONCEPT of ischaemia as a cause of colitis is a relatively new one (Marston et al., 1966). It seems to be an uncommon type of colitis and is certainly much less frequent than ulcerative colitis and segmental colitis due to Crohn's disease. However, it is possible that in large general hospitals, dealing particularly with geriatric patients, ischaemic colitis may be recognized more frequentl...

AIM To determine adiponectin expression in colonic tissue of murine colitis and systemic cytokine expression after melatonin treatments and sleep deprivation. METHODS The following five groups of C57BL/6 mice were used in this study: (1) group I, control; (2) group II, 2% DSS induced colitis for 7 d; (3) group III, 2% DSS induced colitis and melatonin treatment; (4) group IV, 2% DSS induced c...

OBJECTIVES Allergic colitis is often diagnosed clinically in healthy infants with rectal bleeding and often treated with costly hypoallergenic formula. The true prevalence of allergic colitis is unknown. We tested the hypothesis that allergic colitis is overdiagnosed in healthy infants with rectal bleeding. The authors also determined whether rectal bleeding in infants without allergic colitis ...

colitis is an inflammatory disease of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. we were interested to examine the effect of total extract from pycnocycla spinosa boiss. on the treatment of experimental colitis. mediators involved in colonic inflammation are prostaglandins, interleukins, leukotriene as well as an increase in myeloperoxidase...

Cyclosporine may be considered as state of the art treatment for steroid resistant severe ulcerative colitis. Up to 30-40% of the patients with severe ulcerative colitis will fail to respond to intravenous steroid treatment and would require surgical treatment. I report a case of steroid resistant severe ulcerative colitis, which failed to respond to cyclosporine due to presence of cytomegalovi...

Ischemic colitis is generally considered a disease of the elderly. The causes of ischemic colitis include low-flow states due to cardiac dysfunction or hypovolemia and certain medications including estrogen. Here we report a case of ischemic colitis in a 26-year-old woman. She had no specific medical history except taking oral-contraceptives for a long time. The mechanism of estrogen-induced is...