background and objectives: baneh tree or pistacia atlantica subsp. kurdica is an endemic plant of iran which belongs to anacardiaceae family. it has various traditional uses including astringent and anti-diarrheal as well as improving some of the symptoms of gastrointestinal upsets. in this study we decided to investigate the effects of various fractions of baneh gum with different doses in an ...

Amongst extraintestinal manifestations (EIM) occurring in IBD patients, rheumatologic manifestations are the most frequent. Understanding the relationships between arthritis and colitis is a prerequisite to improving the management of these patients. Microbiota of patients with IBD or rheumatologic diseases, like spondyloarthritis (SpA) is modified compared to healthy individual. Thus, we have ...

Dysregulated immune responses to the gut microbiota are believed to be the driving force in the development of inflammatory bowel diseases. Even with combined modern and newer diagnostic technologies, it is difficult to accurately differentiate colonic inflammatory bowel disease, namely ulcerative colitis and Crohn’s colitis. Regardless of current advanced clinical and pathological criteria ava...

Fulminant colitis can be a sequelae of a number of conditions like Salmonellae, Shigella, E. Coli, Yersinia and other bacterial infections. Antibiotic associated pseudomembranous colitis is caused by clostridiuin difficle and can range from mild diarrhoea to fulminant colitis. Furthermore, chronic conditions like ulcerative colitis and Crohn’s disease can cause acute symptoms. Non-specific coli...

the aim of this paper is to introduce new methods of colorectal and anus surgeries. it is not a comprehensive paper and just is a summary of issues related to colon surgeries due to intestinal inflammatory diseases (ulcerative colitis and crohn's disease), and anus cancer. ulcerative colitis usually initiates from rectum and then develops upward to colon. there are three methods of surgery...

The anti-inflammatory actions of vitaminDhave long been recognized and its importance inmodulating colon cancer and colitis development is becoming apparent. The vitamin D receptor (VDR) is downregulated in human ulcerative colitis and colitis-associated cancer (CAC); however, its status in murine models of colitis has yet to be explored. Snail and Snail2, zinc-finger transcription factors regu...

BACKGROUND/AIMS Microscopic colitis is characterized by chronic watery diarrhea with specific pathological changes that can be diagnosed by microscopic examination. We performed immunohistochemical analysis of proinflammatory cytokines to investigate the pathogenic mechanism of microscopic colitis. METHODS This study consisted of six patients with lymphocytic colitis, six patients with collag...

Apart from inflammatory bowel diseases (IBD), there are several other form of colitis that may resemble macroscopically IBD, entering the differential diagnosis. These forms are represented by infectious colitis, ischemic colitis, pseudomembranous colitis, colitis related to diverticular disease, colitis related to mucosal prolapse, drug colitis, allergic colitis, and microscopic colitis. Howev...

Microscopic colitis is a common cause of chronic, nonbloody diarrhea. Microscopic colitis is more common in women than men and usually affects patients in their sixth and seventh decade. This article reviews the etiology and medical management of microscopic colitis. The etiology of microscopic colitis is unknown, but it is associated with autoimmune disorders, such as celiac disease, polyarthr...

Objective: Anti-inflammatory, immuno-modulatory, and antioxidant properties of Moringa oleifera Lam. suggest that it might have beneficial effects on colitis. The present study was performed to investigate the anticolitis effect of Moringa oleifera seeds hydro-alcoholic extract (MSHE) and its chloroform fraction (MCF) on acetic acid-induced colitis in rats. Materials and Methods: Both MSHE and ...