Clinical Prediction Rules (CPRs) are tools that quantify the contribution of symptoms, clinical signs and available diagnostic tests, and in doing so stratify patients according to the probability of having a target outcome or need for a specified treatment. Most focus on the derivation stage with only a minority progressing to validation and very few undergoing impact analysis. Impact analysis...

Károly Mirnics,1,2* Zeljka Korade,3* Dominique Arion,1 Orly Lazarov,4 Travis Unger,1 Melissa Macioce,1 Michael Sabatini,1,2 David Terrano,4 Katherine C. Douglass,1 Nina F. Schor,3 and Sangram S. Sisodia4 Departments of 1Psychiatry, 2Neurobiology, and 3Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, and 4Center for Molecular Neurobiology, University of Ch...

This paper presents TrAVis (Tracking Data Analysis and Visualization Tools), a Web-based system, implemented to assist the participants in the learning process in analyzing the tracking data of ComputerMediated Communication activities. While most of the existing systems in the same genre are exclusively dedicated to the teachers and only a few are accessible by students, TrAVis is objectively ...

the aim of this research is to develop a model of antecedents and consequences of iran exemplary exporters’ competitive intelligence (ci) in order to identify their strengths and weaknesses. for this purpose we discuss position and growth strategies of exporters, effective use of ci, export competitiveness enhancement and sustainable export development. based on conceptual model, knowledge mana...

The present study tested with 142 families a structural model of the interplay of perceived dyadic and collective forms of efficacy within the interdependent family system, and how these different forms of efficacy are structurally related to quality of family functioning and satisfaction with family life. Dyadic parent–child efficacy, dyadic spousal efficacy, and filial efficacy were linked to...

Although there is evidence that non-government health system actors can individually or collectively develop practical strategies to address primary health care (PHC) challenges in the community, existing frameworks for analysing health system governance largely focus on the role of governments, and do not sufficiently account for the broad range of contribution to PHC governance. This is impor...

Hedgehog (Hh) proteins signal by inhibiting the proteolytic processing of Ci/Gli family transcription factors and by increasing Ci/Gli-specific activity. When Hh is absent, phosphorylation of Ci/Gli triggers binding to SCF ubiquitin ligase complexes and consequent proteolysis. Here we show that multiple successively phosphorylated CK1 sites on Ci create an atypical extended binding site for the...

Future pervasive environments will take into consideration physical and digital social relations. Nowadays it is important use to collective intelligence, where the interpretation of context information can be harnessed as input for context-aware applications, especially for group collaboration. The use of collective intelligence represents new possibilities but also new challenges in terms of ...

Freshman and Sophomore classes, sex groups, and age groups. We did not attempt (as Travis2 did) to discover whether the test gave satisfactory results for individuals. For in order to gauge the intelligence of individuals it is generally agreed3 that one kind of test alone is insufficient, and that a series of different tests give better results; and in the second place, tests given to classes ...

We study how several collective operations like broadcast, reduction, scan, etc. can be composed efficiently in complex parallel programs. Our specific contributions are: (1) a formal framework for reasoning about collective operations; (2) a set of optimization rules which save communications by fusing several collective operations into one; (3) performance estimates, which guide the applicati...