The familial occurrence of tumors has been investigated in 389 subjects with colorectal cancer by reviewing the clinical data and the genealogical tree of all patients registered in 1984-1986, in the Local Health District, for malignancies of the large bowel. Among first-degree relatives of the registered patients there were 89 cases of colorectal cancer as opposed to 19 in a hospital-based con...

Narrow-band imaging (NBI) of surface microvessels of colorectal lesions is useful for differentiating neoplasms from non-neoplasms and for predicting histopathological diagnosis. Furthermore, NBI of surface microstructure, or 'surface pattern', is valuable for predicting histopathology in colorectal cancer. The aim of the present study was to investigate whether surface patterns could be used t...

The lung is the most common site for metastasis from colorectal cancer, which is among the most common neoplasms in developed countries. Simultaneous occurrence of pulmonary metastasis of colorectal origin and primary carcinoma has been reported. We describe the case of a 65-year-old man who underwent low anterior resection for colorectal adenocarcinoma in 2007. Follow-up computed tomography re...

Epplein and colleagues (1) reported that the overall Helicobacter pylori (H. pylori) seropositivity was not associated with colorectal cancer risk, and seropositivity to specific H. pylori proteins, particularly the toxin VacA antibodies, may be associated with a higher risk of colorectal cancer and right-sided colon cancers. Remarkably, the serologic test does not discriminate between current ...

BACKGROUND Anthranoid laxatives are the most commonly used purgatives in the therapy of acute and chronic constipation. Recent experimental data and a prospective cohort study provide evidence of a possible risk of anthranoid use for the development of colorectal neoplasms. MATERIALS AND METHODS We performed a prospective case control study at the University of Erlangen to investigate the ris...