Background and aims: Congenital anomalies are as the major causes of stillbirths, neonatal death, disability and childhood health problems all over the world. The aim of this study was to determine the incidence and pattern of congenital anomalies in newborn during the first 24 hours of life in Shahid-Madani hospital, Azarshahr, Tabriz, during two periods 2002-2003 and 2...

this case report presents a case of fanconi’s anemia with an unusual thumb polydactyly in a 2-year old boy. the extra thumb had no nail, nail bed and distal phalanx. the extra thumb had no active motion.the duplication of the thumb occurred at the carpometacarpal joint but its morphology did not match with any classification described for thumb polydactyly. although his thumb polydactyly was ap...

OBJECTIVE To validate the estimates of Global Burden of Disease (GBD) due to congenital anomaly for Europe by comparing infant mortality data collected by EUROCAT registries with the WHO Mortality Database, and by assessing the significance of stillbirths and terminations of pregnancy for fetal anomaly (TOPFA) in the interpretation of infant mortality statistics. DESIGN, SETTING AND OUTCOME M...

Unexpected and puzzling variations in bronchial anatomy might be discovered during bronchoscopy. The occurrence of congenital tracheobronchial anomaly is estimated to range between 1% and 12% of the overall population.1 We present 2 rare cases of congenital bronchial anomaly that were discovered during bronchoscopy and that emphasize the value of computed tomogram (CT) in diagnosing congenital ...

short rib polydactyly syndrome (srps) is a very rare congenital anomaly that is classified into four subtypes. it is an autosomal recessive inherited disease. we report a case of this syndrome without a previous family history of congenital defects.

background: distraction osteogenesis (ds) is currently an important technique for lengthening shortened bones of the hand and foot. authors report their experience in applying ds for various conditions of the hand and foot using a distractor that the senior author has designed. materials and methods: records of patients who underwent ds for hand and foot conditions in a private clinic were retr...

OBJECTIVES To evaluate the risk of major congenital anomaly associated with first-trimester exposure to insulin analogues compared with human insulin in offspring of women with pregestational diabetes. DESIGN AND SETTING A population-based cohort of women with pregestational diabetes (n=1661) who delivered between 1996 and 2012 was established retrospectively from seven European regions cover...

BACKGROUND Congenital anomalies are more common in twins than singletons but in the majority, aetiology is not known. Our aim was to test the hypothesis that survivors of an early loss in a multiple conception, compared with all singletons, are at increased risk of congenital anomaly. METHODS Data were abstracted from the UK population-based Northern Multiple Pregnancy Register and Northern C...