BACKGROUND Cerebral contusions have a 51% incidence of evolution in the first hours after injury. Evolution is associated with clinical deterioration and is the reason for ICP monitoring or surgical intervention. We sought to define CT features that predict cerebral contusion evolution. METHODS Patients treated for cerebral contusion who had 2 CT scans within 24 hours after injury were evalua...

OBJECTIVES Lung contusion is a major risk factor for the development of acute respiratory distress syndrome. We set to determine the role of toll-like receptor 3 and the binding of double-stranded RNA in the pathogenesis of sterile injury following lung contusion. DESIGN Toll-like receptor 3 expression was analyzed in postmortem lung samples from patients with lung contusion. Unilateral lung ...

Lung contusion is an entity involving injury to the alveolar capillaries, without any tear or cut in the lung tissue. This results in accumulation of blood and other fluids within the lung tissue. The excess fluid interferes with gas exchange leading to hypoxia. The pathophysiology of lung contusion includes ventilation/perfusion mismatching, increased intrapulmonary shunting, increased lung wa...

OBJECT Although it is generally acknowledged that a sufficient cerebral perfusion pressure (CPP) is necessary for treatment of severe head injury, the optimum CPP is still a subject of debate. The purpose of this study was to investigate the effect of various levels of blood pressure and, thereby, CPP on posttraumatic contusion volume. METHODS The left hemispheres of 60 rats were subjected to...

background hemorrhagic progression of a contusion (hpc) is one of the main problems in neurosurgery, which is associated with several adverse effects and increasing the risk of mortality. the present study investigated the effect of transfusion of fresh frozen plasma (ffp) in the prevention of hpc. material and methods in this randomized clinical trial, 100 patients with cerebral contusion were...

Quantification and analysis of brain contusion was initially done in 1970’s followed by 2005. They derived brain contusion index based on parenchymal depth and surface distribution of contusion over brain. We conducted this study with the objectives of whether severity of contusion index determines Post trauma survival, is there a region specific contusion which determines Post trauma survival ...

Persistent profound visual loss following contusion of the globe or ocular adnexae has been well documented, the visual loss being attributed to haemorrhage into, or contusion of, the optic nerve, or to interference with the blood supply of the eye. The patient described below presented after a contusion of the eye and orbit, with the clinical picture of ischaemic optic neuropathy presumably re...