Observations of the mollusc-hunting cone snail Conus textile during feeding reveal that prey are often stung multiple times in succession. While studies on the venom peptides injected by fish-hunting cone snails have become common, these approaches have not been widely applied to the analysis of the injected venoms from mollusc-hunters. We have successfully obtained multiple injected venom samp...

conclusions in most cases, the conus artery can be visualized in cardiac ct. a description of the conus artery should be a part of the standard clinical coronary ct angiography description. objectives to examine whether it is possible to visualize the conus artery in multi-slice computed tomography (ct). patients and methods in 79 consecutive patients (aged 56 ± 12.9 years; 13 women), 64-slice ...

We carried out a definition of the species group to which Conus praecellens A. Adams 1854 belongs using a combination of comparative morphological data, molecular phylogeny based on standard genetic markers and toxinological markers. Prior to this work, Conus praecellens was generally postulated to belong to a clade of similarly high-spired, smaller Conusspecies such as Conus pagodus Kiener, 18...

A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid chromatography, was applied to screen animal venoms for nicotinic acetylcholine receptor like (nAChR) affinity by using the acetylcholine binding protein, a mimic of the nAChR. The potential of this microfluidic platform is demonstrated by profiling ...

The afterdischarge of Aplysia bag cell neurons has served as a model system for the study of phosphorylation-mediated changes in neuronal excitability. The nature of the depolarization generating the afterdischarge, however, has remained unclear. We now have found that venom from Conus textile triggers a similar prolonged discharge, and we have identified a slow inward current and corresponding...

The biology of modern Conidae (cone snails)--which includes the hyperdiverse genus Conus--has been intensively studied, but the fossil record of the clade remains poorly understood, particularly within an evolutionary framework. Here, ultraviolet light is used to reveal and characterize the original shell coloration patterns of 28 species of cone snails from three Neogene coral reef-associated ...