The central nervous system depressant activity of the crude methanol extract (REC) and fractions (RE1, RE2, and RE3) of Russelia equisetiformis were evaluated in mice using the following models: amphetamine-induced stereotypy, picrotoxin-induced convulsion and phenobarbitone sleeping time. At 200-400 mg/kg, REC significantly increased phenobarbitone-sleeping time [P < 0.05] in a dose- dependent...

In the present study, Solanum melongena Linn. (Brinjal; Solanaceae), was evaluated for its antiepileptic activity against experimental seizures. The roots ethanolic extract of Solanum melongena protected mice against tonic convulsion induced by maximal electroshock, Pentylenetetrazole and Picrotoxin. It was found that ethanolic extract up to a dose of 300 mg/kg p.o. decreased the duration of to...

introduction: febrile convulsions occur in young children when there is a rapid increase in their body temperature. it affects up to 1 in 20 children between the ages of one and four but can affect children between six months and about five years old.  previous studies have showed relationship between low serum sodium and calcium level and recurrence of febrile convulsions. this study designed ...

background epilepsy is a chronic neurological disease with the prevalence of around one percent. despite the introductions of several anti-epileptic drugs, around 1/3 of epileptic patients are resistant to the anti-epileptic medications. objectives considering the evidence regarding the anti-oxidant action of vitamin e and its beneficiary effect in the treatment of epilepsy, we investigated the...

febrile convulsion (fc) is the most common seizure disorder in young children. different predisposing factors have been suggested to enhance the susceptibility to febrile seizure and its recurrence. the main objective of this study was to identify the adverse effect of electrolytes disturbance in fc and its recur-rence. the medical records of 175 children with convulsive disorders were reviewed...

background and objective: febrile convulsions (fc) are the most common seizure disorder in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, and protein and glucose levels in cere-brospinal fluids (cfs) of children hospitalized with fc. methods: in this cross s...

background and objective: regarding the prevalence of epilepsy in human society and with respect to insufficiency of usual treatments, new strategies and methods for medical treatment of epileptic patients are necessary. as nmda receptor antagonists are the most prominent anti-epileptic drugs, in the present study, we synthesized and investigated anti-epileptic effect of a new piperidine deriva...

background and objective: febrile convulsions (fc) are the most common seizure disorders in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (cfs) of children that were hospitalized with fc. methods: in this c...

objective this study was conducted to determine the frequency of urinary tract infection(uti) among children with febrile convulsion (fc). materials & methods we analyzed the hospital records of 137 children who had been admitted to thepediatric ward from march 2004 to february 2007 because of fc. informationsuch as age, sex, developmental status, type of fc, family history of seizure,urine sam...