Genome-Wide Association Studies (GWAS) have identified genetic variants contributing to the risk of cardiovascular disease (CVD) at the chromosome 9p21 locus. The chromosome 9p21 is an important susceptibility locus for several multifactorial diseases like ischemic stroke, aortic aneurysm, type 2 diabetes mellitus and coronary artery disease (CAD). F7 gene because of its role in activating the ...

spontaneous coronary artery dissection is a rare cause of acute coronary syndrome and sudden cardiac death. we report coronary artery dissection in a 36-year-old woman with retrosternal chest pain 2 weeks after abortion. electrocardiography showed st elevation in leads v2-v4 and st depression in the inferior leads. lab data were normal. cardiac catheterization showed a suspicious thrombotic les...

Dobutamine stress echocardiography (DSE) has been widely used as a diagnostic and prognostic modality in the management of stress. DSE is associated with limited complications and adverse effects on the health of patients. In this case report, we described a 42-year-old female patient with dobutamine-induced coronary artery spasm with history of exertional dyspnea, which had deteriorated recent...

Coronary aneurysms are typically seen in association with Kawasaki disease and only in rare instances, they are reported to be congenital or idiopathic. Here we report a case of a five year old boy who was found to have an idiopathic right coronary artery aneurysm. He presented with complaints of recurrent respiratory tract infections. His examination and investigations did not reveal any of th...

background coronary artery disease is the single most important cause of mortality and morbidity in diabetic patients. electrocardiographic stress test is a non-invasive modality to screen significant coronary involvement in minimally symptomatic diabetics. objectives we investigated the positive predictive value (ppv) of this test in comparison with coronary angiography. materials and methods ...

Abstract Background: Illness perception can affect health-related behaviors and disease outcomes. Objectives: To determine the effect of an educational intervention of improving illness perception on some modifiable risk factors of coronary artery disease. Methods: In this clinical trial, 100 patients undergoing coronary angiography that met the inclusion criteri...

the left ventricular aneurysm is one of the most significant complications of myocardial infarction and is defined as the expansion of the ventricular wall. the coronary artery aneurysm is characterized by an abnormal dilation of the localized portion of the coronary artery, and its main cause is atherosclerosis. we herein report an unusual case of coronary artery and left ventricular aneurysms...