Diastolic pressure-length relationships of an ischemic region of the canine left ventricle were measured over a six-hour period following left anterior descending coronary artery ligation, and their evolution was compared with the extent of systolic aneurysmal bulging. Normalized ischemic segment length excursion, which after coronary artery ligation may be taken as a measure of systolic aneury...

Van den Bos, Ewout J., Barend M. E. Mees, Monique C. de Waard, Rini de Crom, and Dirk J. Duncker. A novel model of cryoinjury-induced myocardial infarction in the mouse: a comparison with coronary artery ligation. Am J Physiol Heart Circ Physiol 289: H1291–H1300, 2005. First published April 29, 2005; doi:10.1152/ajpheart.00111.2005.—Mouse myocardial infarction (MI) models are frequently used re...

BACKGROUND Blunt thoracic trauma can rarely result in coronary artery injury. Blunt trauma can result in occlusion of any of the coronary arteries or can lead to its rupture and bleeding. Traumatic coronary artery occlusion can lead to myocardial infarction, while its rupture and bleeding can result in hemopericardium and cardiac tamponade, and can be rapidly fatal. Survival after coronary arte...

In 14 mongrel dogs, refractory periods were determined in nonischemic and acutely ischemic zones of myocardium during control conditions, 15 minutes after coronary ligation, and 10 and 20 minutes after a procainamide infusion. Following coronary ligation, refractory periods in the nonischemic area remained unchanged (100.8% of control) while in the ischemia area they decreased to 88.6% of contr...

BILATERAL ligation of the internal mammary arteries was proposed by Fieschi as a simple surgical means of treating patients with coronary artery disease. The procedure aims to increase the blood pressure in the pericardiophrenic branches of the internal mammary arteries and, thereby enhancing coronary anastomoses to the myocardium. Observations made on patients have been conflicting,' as have t...

Saccular coronary artery aneurysm, associated with coronary artery fistula, is a very rare condition. A 48-year-old woman was referred to our hospital for the evaluation of an abnormal shadow on the left cardiac border from a chest X-ray film during regular medical health examination. A huge saccular aneurysm with organized thrombi in the proximal left anterior descending artery (LAD) and coron...

• The mechanism of shock following acute myocardial infarction is still controversial. Xumerous investigators have applied techniques such as: (a) ligation of the different branches of the coronary arteries," (b) chemical or traumatic methods to produce myoeardial injury/" and (c) introduction of einbolizing particles into the coronary circulation." The results are conflicting, largely because ...

Coronary artery fistulae are uncommon, reported in 0.25% of patients undergoing coronary angiography. Two patients with congenital coronary artery fistula and coronary artery disease who presented with symptoms of exacerbated congestive heart failure out of proportion to their atherosclerotic burden were successfully treated by epicardial fistula ligation and coronary artery bypass grafting wit...

Abstract CD69 depletion from the lymphoid compartment promotes a Th17/Treg imbalance and exacerbates development of atherosclerosis. As atherosclerosis is trigger myocardial infarction, we have analyzed role in Treg cells after a) permanent occlusion left-anterior-descending coronary artery (LAD-ligation) mice, b) angiography two cohorts acute infarction (MI) patients. Our data show that expres...