arrhythmogenic right ventricular dysplasia/cardiomyopathy (arvd/c) is a congenital cardiac disease with myocardial involvement, most probably right ventricular (rv) dysfunction, accounting for 20% of sudden cardiac deaths. characterized by the fibro-fatty infiltration of the rv free wall, arvd/c presents in adolescents with ventricular arrhythmias and heart failure symptoms and as biventricular...

the left ventricular aneurysm is one of the most significant complications of myocardial infarction and is defined as the expansion of the ventricular wall. the coronary artery aneurysm is characterized by an abnormal dilation of the localized portion of the coronary artery, and its main cause is atherosclerosis. we herein report an unusual case of coronary artery and left ventricular aneurysms...

background: it is not clear whether the latest activation sites in the left ventricle (lv) are matched with infracted regions in patients with ischemic cardiomyopathy (icm). we aimed to investigate whether the latest activation sites in the lv are in agreement with the region of akinesia in patients with icm.   methods: data were analyzed in 106 patients (age = 60.5 ± 12.1 y, male = 88.7%) with...

background: differences in the quantity and distribution of coronary veins between patients with ischemic and non-ischemic cardiomyopathy might affect the potential for the left ventricular (lv) lead targeting in patients undergoing cardiac resynchronization therapy (crt). in the current study, we assessed and compared the suitability of the coronary venous system for the lv lead placement in i...

Disorders of the Pericardium Pericardial Effusion Pericarditis Acute Pericarditis Chronic Pericarditis With Effusion Constrictive Pericarditis Coronary Heart Disease Coronary Circulation Pathogenesis of Coronary Heart Disease Chronic Ischemic Heart Disease Stable Angina Variant Angina Silent Myocardial Ischemia Acute Coronary Syndromes Unstable Angina/Non–ST-Segment Elevation Myocardial Infarct...

background: cardiac rehabilitation has been recognized as one of the most effective strategies for managing cardiovascular indices as well as controlling the cardiovascular risk profile, in particular after coronary artery bypass graft surgery (cabg). however, the effect of this program on right ventricular function following cabg is unclear. the aim of this study was to evaluate the impact of ...

Cardiovascular diseases (CVD), a group of that affect the heart and blood vessels have posed high morbidity rate to humans, with second-high mortality after cancer. These include hypertension, coronary artery disease, cardiac dysrhythmias, cerebrovascular valvular cardiomyopathies, peripheral vascular congenital abnormalities. been observed people older age higher susceptibility in male than fe...

Cardiomyopathies can generally be categorized into two groups, based on World Health Organization guidelines: extrinsic and intrinsic. In extrinsic cardiomyopathies the primary pathology is outside the myocardium. Most cardiomyopathies are extrinsic, because the most common cause is ischemia. Intrinsic cardiomyopathies is weakness in the muscle of the heart that is not due to an identifiable ex...

Expression of the Wilms' tumor gene Wt1 in the epicardium is critical for normal heart development. Mouse embryos with inactivated Wt1 gene have extremely thin ventricles, which can result in heart failure and death. Here, we demonstrate that Wt1 can be activated in adult hearts by local ischemia. Wt1 mRNA was increased more than twofold in the left ventricular myocardium of rats between 1 day ...

regular participation in intensive physical exercise is associated with electro-morphological changes in the heart.   this benign process is called athlete’s heart. athlete’s heart resembles few pathologic conditions in some aspects. so differentiation of these conditions is very important which otherwise may lead to a catastrophic event such as sudden death. the most common causes of sudden de...