Dimension reduction is critical in many areas of data mining and machine learning. In this paper, a Covariance-preserving Projection Method (CPM for short) is proposed for dimension reduction. CPM maximizes the class discrimination and also preserves approximately the class covariance. The optimization involved in CPM can be formulated as low rank approximations of a collection of matrices, whi...

Three health symptom checklists were used to measure physical health concerns among university women in relation to prior child physical maltreatment (CPM) (20%, n = 153) and child sexual abuse (CSA) (19%, n = 143). A history of CPM was related to all three general areas of health concerns as well as to many of the specific subscales comprising the measures (e.g., muscular-skeletal symptoms and...

An 84-year-old lady was treated for hyperosmolar hyperglycaemia with IV insulin, fluids and catheterisation for fluid balance monitoring. Trial without catheter failed as the patient complained of new-onset urinary incontinence and lack of awareness of bladder filling. In light of her breast cancer history, we excluded cauda equina. Ultrasound KUB showed an enlarged bladder. Whole-body MRI reve...

BACKGROUND Adequate and intensive rehabilitation is an important requirement for successful total knee arthroplasty. Although research suggests that Continuous Passive Motion (CPM) should be implemented in the first rehabilitation phase after surgery, there is substantial debate about the duration of each session and the total period of CPM application. A Cochrane review on this topic concluded...

A potential role for the renin-angiotensin system (RAS) in the development and/or maintenance of hypertension in the genetic model of rat hypertension, spontaneously hypertensive rats (SHR), has been suggested by studies indicating that treatment of immature animals with angiotensin-converting enzyme (ACE) inhibitors prevents subsequent development of hypertension. Because young SHR also demons...

We present the Convex Polytope Machine (CPM), a novel non-linear learning algorithm for large-scale binary classification tasks. The CPM finds a large margin convex polytope separator which encloses one class. We develop a stochastic gradient descent based algorithm that is amenable to massive data sets, and augment it with a heuristic procedure to avoid sub-optimal local minima. Our experiment...

Spectrally e cient Continuous Phase Modulation for a speci c narrow spectrum requirement mask and a prescribed information bit rate has been designed and analyzed in terms of the minimum Euclidean distance and simulated symbol error probability for the AWGN channel. The performance of a low complexity sub-optimum detector based on an approximate lter bank and a reduced state Viterbi decoder for...

Bcl-2 is a potent suppressor of apoptosis, and its overexpression contributes to tumorigenesis in many types of human cancers. To test the possibility of modulating Bcl-2 function as an anticancer strategy, a cell permeable Bcl-2 binding peptide, cell permeable moiety (cpm)-1285, was designed by chemically attaching a fatty acid to a peptide derived from the proapoptotic protein Bad. cpm-1285 e...

Abstract—We derive upper bounds on the capacity of an additive Gaussian noise channel with continuous phase modulation (CPM). We propose an MMSE approximation to Laurent’s linear decomposition using an arbitrary number of filtered, linearly modulated pulses. Using this linear modulation structure, we derive capacity bounds for both white and colored noise channels with CPM modulation by showing...

Central pontine myelinolysis (CPM) is a demyelinating disorder characterized by the loss of myelin in the center of the basis pons, and is mainly caused by the rapid correction of hyponatremia. We report the case of a young woman who presented with gait disturbance and alcohol withdrawal, and who was eventually diagnosed with CPM. Generally, the cause and pathogenesis of CPM in chronic alcoholi...