BACKGROUND Cell-penetrating peptides (CPPs) can act as carriers for therapeutic molecules such as drugs and genetic constructs for medical applications. The triggered release of the molecule into the cytoplasm can be crucial to its effective delivery. Hence, we implemented and characterized laser interaction with defined gold nanoparticle agglomerates conjugated to CPPs which enables efficient ...

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most common urologic morbidity in men younger than 50 years and is characterized by a diverse range of pain and inflammatory symptoms, both in type and severity, that involve the region of the pelvis, perineum, scrotum, rectum, testes, penis, and lower back. In most patients, pain is accompanied by inflammation in the absence of ...

OBJECTIVE The current study investigated the internal structure and external relations of the Children's Psychological Processes Scale (CPPS). METHOD Principal components analysis and exploratory factor analysis were conducted. Concurrent validity studies were also completed with the Behavior Rating Inventory of Executive Function (BRIEF) and Woodcock-Johnson III Tests of Cognitive Abilities ...

Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g. plasmid DNA and (si)RNA, opening doors for new therapeutics. Although several hundreds of CPPs are already described in the literature, only a few commercial applications of CPPs are currently available. Cell...

Choroid plexus papilloma (CPP) is a rare, benign epithelial brain tumor of the nervous system seen particularly in infants. Familial cases are extremely uncommon. Some other form of malignant tumors was noted in the relatives of patients with CPPs, and some genetic defects regarding this coincidence were reported in the literature. These neoplasms are occasionally bilateral and hydrocephalus is...

Traditional measures of dysphonia vary in their reliability and in their correlations with perceptions of grade. Measurements of cepstral peak prominence (CPP) have been shown to correlate well with perceptions of breathiness. Because it is a measure of periodicity, CPP should also predict roughness. The ability of CPP and other acoustic measures to predict overall dysphonia and the subcategori...

With the development of smart grid technology, there has been an increasingly strong tendency towards the integration between the aspects of power and communication. The traditional power system has gradually transformed into the cyber-physical power system (CPPS), where co-simulation technologies can be utilized as an effective measure to describe the computation, communication, and integratio...

Cancer has become one of the leading causes of mortality globally. The major challenges of conventional cancer therapy are the failure of most chemotherapeutic agents to accumulate selectively in tumor cells and their severe systemic side effects. In the past three decades, a number of drug delivery approaches have been discovered to overwhelm the obstacles. Among these, nanocarriers have gaine...

The complex workflows and interactions between heterogeneous entities in Cyber-Physical Production Systems (CPPS) call for the use of context-aware computing technology to operate effectively meet order requirements a timely manner. In addition objective due date, resource contention production processes, CPPS may enter undesirable states. states, all or part activities are waiting states block...