BACKGROUND The incomplete repair (IR) model expresses the cell repair effect from radiation-induced damage over time, which is given little consideration in actual treatment planning. By incorporating the IR model into the normal tissue complication probability (NTCP), the accuracy and safety of treatment plan evaluations concerning the effect of repair can be improved. This study aims to evalu...

Two adults, 31 and 20 years of age, developed supratentorial metastasis 3½ years and 11 months, respectively, after gross total removal of their posterior fossa medulloblastoma. The first case developed spinal metastasis as well. Both had undergone craniospinal irradiation. Case 1 underwent laminectomy and case 2 underwent craniotomy because their presenting symptoms required so.

PURPOSE To determine the patient, tumor, and treatment characteristics of patients with pilocytic astrocytoma (PA) and leptomeningeal dissemination (LMD). METHODS AND MATERIALS A PubMed search of English-language studies pertaining to PA with LMD was performed using a combination of keywords that included juvenile pilocytic astrocytoma, low-grade astrocytoma, low-grade glioma, leptomeningeal ...

230 2013 Mayo Foundation for Medical Education and Research. Siyong Kim, PhD, owns interests of Medical Tool and Technology, LLC. The other authors have no conflicts of interest to disclose. Submitted November, 27, 2013, Accepted December, 6, 2013 Corresponding Author: Jennifer L. Peterson, Department of Radiation Oncology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA Tel: +1-904...

New advances in radiation therapy for children allow increased conformability and reduced doses to non-target tissues. We report our experience in treating a 4-year-old child with craniospinal tomotherapy after surgery of the primary tumor, a supratentorial primitive neuroectodermal tumor. The tomotherapy plan was compared with conventional craniospinal irradiation, 3D conformal radiation thera...

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