We have studied the micellization of surfactants SDS, CTAB and tweens-80 using a series of Ethylene glycol/water and formamide/water mixed solvents using surface tension, viscosity and conductance measurements. The results are compared with those reported in pure water for the same surfactants. The critical micelle concentration (cmc) shifts to lower values upon increasing the ratio of Ethylene...

Marine invertebrate deposit feeders secrete surfactants into their gut fluid in concentrations sufficient to induce micelle formation, enhancing solubilization of sedimentary lipids. We isolated and identified 3 related surfactant molecules from the deposit-feeding polychaete lugworm Arenicola marina. Surfactants were isolated and separated by a combination of solvent extraction and thin-layer ...

A novel polymer-drug conjugate was prepared by the chemical reaction between the copolymer Pluronic P123 and the docetaxel via a pH sensitive hydrazone bond. These pluronic P123-docetaxel (DTX) conjugates (P123-DTX) could form the stable drug-loaded materials that can self-assemble into the defined nano-micelles in aqueous solution because of their obvious amphiphilic property and low critical ...

Polymer-surfactant interactions in aqueous solutions of a hydrophobically modified polymer, poly(maleic acid/octyl vinyl ether) (PMAOVE), with sodium dodecyl sulfate (SDS) were studied using surface tension, viscosity, electron paramagnetic resonance spectroscopy, and fluorescence spectroscopic techniques. When the anionic surfactant SDS was added to the aqueous solutions of the similarly charg...

Surfactants are often used to improve the solubility of a compound for dissolution studies in aqueous media. Having observed non-linear enhancement with increasing surfactant concentration, this study investigated effect poorly soluble, zwitterionic, moderately lipophilic drug, Compound A, on critical micelle concentration (CMC)of sodium lauryl sulfate (SLS) phosphate buffer. A force tensiomete...

The structure of micelles formed by nonionic polyoxyethylene alkyl ether nonionic surfactants, C n E m , in the room-temperature ionic liquid, ethylammonium nitrate (EAN), has been determined by small-angle neutron scattering (SANS) as a function of alkyl and ethoxy chain length, concentration, and temperature. Micelles are found to form for all alkyl chains from dodecyl through to octadecyl. D...

The objective of this study was to model the critical micelle concentration (cmc) of nonionic surfactants in nonaqueous systems using the UNIFAC group contribution method. For the prediction of the cmc the phase separation approach was used, where the micellar phase is approximated as a second liquid phase resulting from the liquid-liquid equilibrium between the solvent and the surfactant, with...

We investigate micelle formation in a system containing two or more different amphiphiles with different geometries using a stochastic molecular-dynamics (MD) simulation method. For a binary system containing two amphiphiles, we calculate the critical micelle concentration (CMC) and cluster distribution for the mixture at several mole fractions and compare the simulation results with those pred...

Large quantities (>3 g) of a new series of alkyl uronates were synthesized in two steps from commercial methyl hexopyranosides. Firstly, several tens of grams of free methyl α-d-glucopyranoside were selectively and quantitatively oxidized into corresponding sodium uronate using 2,2,6,6-tetramethyl-1-piperidinyloxy free radical (TEMPO)-catalyzed oxidation. Hydrophobic chains of different length ...

Micellization of the ionic surfactant sodium hexyl sulfate has been studied using atomistic explicit-solvent molecular dynamics simulations with and without excess NaCl or CaCl(2). Simulations were performed at surfactant loadings near the critical micellization concentration. Equilibrium micelle size distributions and estimates of the critical micellization concentration obtained from the simu...