Crocus sativus is a triploid sterile plant with red stigmas belonging to family of Iridaceae, and sub Crocoideae. Crocin, picrocrocin, safranal are three major carotenoid derivatives that responsible for color, taste specific aroma Crocus. Saffron flowers harvested manually used as spice, dye or medicinal applications. The natural propagation rate most geophytes including saffron relatively low...

Crocin( Crocetin di-gentiobiose ester ) is the chemical constituent isolated from the Saffron, the dried trifid stigma of the plant Crocus sativus L. and also from the fruits of Gardenia(Gardenia jasminoides Ellis) It is found to be effective as antiproliferative, anti-oxidant, learning and memory enhancer, brain neurodegenerative disorder, sperm cryoconservation, biosurfactant, alzheimer disor...

Background & Aim: Saffron extract is widely used in the food industry. Saffron (Crocus sativus L.) stigmata contain rare water-soluble carotenoids and the major one is Crocin and this compound have a antitumor in rate and human losomi cells and other model of cancer cells.  In this research, we are study on effects of cultivation condition and storage on dried stigmata of   Crocus ...

Background & Aim: Saffron extract is widely used in the food industry. Saffron (Crocus sativus L.) stigmata contain rare water-soluble carotenoids and the major one is Crocin and this compound have a antitumor in rate and human losomi cells and other model of cancer cells.  In this research, we are study on effects of cultivation condition and storage on dried stigmata of   Crocus ...

safranal, the main component of crocus sativus essential oil, exhibits different pharmacological activities. in this study, the effects of safranal, on blood pressure of normotensive and desoxycorticosterone acetate (doca) - salt induced hypertensive rats in chronic administration were investigated. three doses of safranal (1, 2 and 4 mg/kg/day) and spironolactone (50 mg/kg/day) were administra...

this study was designed to investigate the therapeutic effects of saffron (crocus sativus l) and its main constituent crocin on neuropathic pain behavioral responses induced by chronic constriction injury (cci) in rats. adult male wistar rats (200 to 250 g) were randomly assigned into 5 groups: sham + saline, cci + saline, cci+ saffron (30 mg/kg), cci +crocin (15 mg/kg) and cci + crocin (30 mg/...

many cultures have developed folk herbal remedies for various symptoms of mental illness. an evidence base now is being developed for some of these “alternative” herbal remedies. there has been an increase in the number and proportion of clinical trials of complementary medicine, which suggests a trend toward an evidence-based approach. this review presents the scientific information regarding ...