crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

background: there is evidence that pulmonary function abnormalities are present in patients with inflammatory bowel disease (ibd). the aim of this case-control study was to assess the frequency of pulmonary dysfunction in patients with ibd. materials and methods: pulmonary function of 37 patients with ibd (8 with cd and 29 with uc) without any known pulmonary disease was tested by body-box plet...

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

the association of celiac disease and type i diabetes mellitus has been known for some time. this study was undertaken to investigate the prevalence of celiac disease (cd) in diabetic children and adolescents. eighty-seven patients (44 females, 43 males) aged 2- 18 years, with type i diabetes participated in this study. a group of 87 healthy unrelated girls and boys matched for age and gender s...

aim : the aim of this study was to search for metabolic biomarkers of crohn’s disease (cd). background : crohn's disease (cd) is a type of inflammatory bowel disease that causing a wide variety of symptoms. cd can influence any part of the gastrointestinal tract from mouth to anus. cd is not easily diagnosed because monitoring tools are currently insufficient. thus, the discovery of proper meth...

aim : this retrospective study is aimed to review demographic and clinical characteristics of ibd to elucidate the probable factors associating with ibd development in taleghani hospital in iran since 2001 during a 12-year-period.   background : ulcerative colitis (uc) and crohn’s disease (cd) are two major idiopathic entities of inflammatory bowel disease (ibd). previous studies have reported ...

background there are few reports from iran about the epidemiology and clinical features of inflammatory bowel disease (ibd). this study aims to determine the epide­miologic profile and clinical features of ibd in northwest iran referral centers. methods in a cross-sectional setting, we evaluated 200 patients with definitive diagno­ses of ibd who referred to tabriz educational hospitals during t...

background this study aimed to explore demographic characteristics and clinical presentations of celiac disease (cd) in northeastern iran. methods this was a cross-sectional retrospective study of 193 adults with cd who presented to mashhad university gastroenterology clinic between 2008 and 2013. patient data that included mode of presentation and the presence of any concomitant illnesses were...

Celiac disease (CD) is a systemic immune-mediated disorder caused by the dietary gluten in individuals who are genetically susceptible to the disease. In fact, CD is a T cell-mediated immune disease in which gluten-derived peptides activate the lamina propria CD4+ Teff cells, and these T-cell subsets can cause the intestinal tissue damages. Also, there are additional subsets of CD4+ T cells wit...

background: celiac disease (cd), as an autoimmune disease has initiated since ingestion of food containing gluten. constant intolerance to gluten causes damages of the small intestinal mucosa. one reason of mal-absorption in children and infants is cd. additionally, about 75% of newly identified patients with cd have low bone mineral density (bmd). many factors have role in metabolic bone disea...