despite recent innovations in the laboratory diagnosis of bacterial from nonbacterial meningitis, solid data-necessary for early determination of bacterial meningitis (bm) before organism growth in the culture medium-are missing. therefore cerebrospinal fluid (csf) lactate levels were evaluated as a possible means of differentiating the two clinical entities. this was a retrospective study. pat...

objective(s): granulocyte-colony stimulating factor (g-csf) is used in clinical practice for the treatment of neutropenia and to stimulate generation of hematopoietic stem cells in bone marrow donors. in the present study, the ability of g-csf in mobilizing exogenous bone marrow stem cells (bmscs) from peripheral blood into the brain was tested. we for the first time injected a small amount of ...

background: proposing a strategy for sellar reconstruction in endoscopic transsphenoidal transsellar approach for pituitary adenoma. methods: 240 patients with pituitary adenoma underwent pure endoscopic endonasal transsphenoidal surgery. intra-operative csf leaks were classified as grade 0, no observable leak grade 1, csf dripping through an arachnoid membrane defect of less than 1 mm and grad...

G-CSF and GM-CSF play important roles in regulating neutrophil production, survival, differentiation, and function. However, we have shown previously that G-CSF/GM-CSF double-deficient [knockout (KO)] mice still develop a profound neutrophilia in bone marrow and blood after infection with Candida albicans. This finding suggests the existence of other systems, which can regulate emergency neutro...

Abstract BACKGROUND CSF-CTC analysis through the CellSearch® platform has been studied as a diagnostic and prognostic tool for LM from solid tumors. CSF-ctDNA can be detected in and/or BM, with unclear significance. We aimed to evaluate CSF-CTCs predictors of diagnosis survival BM. METHODS retrospectively reviewed charts patients tumors who underwent ctDNA evaluation same lumbar puncture betwee...