Carboxamidomethyl derivatives of sperm whale metmyoglobin were prepared by reaction at pH 6.8 with iodoacetamide. The modified protein is similar to previously studied carboxymethyl preparations and shows many of the properties of the native, unmodified protein. Preparations were obtained with compositions in the following ranges, expressed as moles of histidine derivative per mole of protein: ...

The binding of cupric or zinc ion by sperm whale metmyoglobin appears to involve imidazole groups of histidyl residues (4, 5) that occur well removed from the NH2 terminus (6). The binding of each cupric ion by metmyoglobin is accompanied on the average by the displacement of one or more protons beyond that that may be borne by the imidazole group, presumably from peptide amide nitrogen atoms (...

Background & Aims of the Study: Antibiotics are pharmaceutical compounds which are stable in the environment and their discharge without treatment can cause pollution of the environment. The current study aimed to assess the efficicacy of cupric oxide nanoparticles (CuO-NPs) as another kind of adsorbent for the removal of penicillin G (PG) from its aqueous media, as well as kinetic analysis of ...

Incorporation of copper species into silica matrix was performed by the sol-gel method. Copper ions and copper particles were doped using two different copper sources; Cu(NO3)2.3H2O and copper particles chemically synthesized.The particles of copper metallic, cuprous and cupric oxide were prepared and the synthesis and characterizations of copper species were compared together. On the other han...

Three different orientations of non-blue, type 2 cupric complexes on DNA fibers are obtained from EPR data. The cupric complex of bleomycin, CuBlm, binds as described previously (Shields, H., McGlumphy,C., and Hamrick, P., J., Jr. (1982) Biochim. Biophys. Acta 697, 113-120), except possibly with more restricted motion. The square plane of CuBlm makes an angle of about 65 degrees with the fiber ...

In this article, reduced graphene oxide (RGO)/carboxymethyl chitosan (CMC) composites (RGO/CMC) were synthesized by a hydrothermal method through in-situ reduction and modification of graphene oxide (GO) in the presence of CMC. An electrochemical sensor for the determination of Cu(II) by differential pulse anodic stripping voltammetry (DPASV) was constructed by an electrode modified with RGO/CM...