Cure models are survival models basically developed to estimate the proportion of patients cured in a clinical trial. These models estimate the cured proportion and also the probability of survival. Cure models are a special type of survival analysis model where it is assumed that there are a proportion of subjects who will never experience the event and thus the survival curve will eventually ...

Given the challenge of delivering complex, expensive and potentially harmful antiretroviral therapy (ART) on a global level, there is intense interest in the development of short-term, well-tolerated regimens that allow individuals to interrupt therapy indefinitely without experiencing a rebound in viremia. This so-called "cure" or "remission" might be due to complete eradication of all replica...

Symbiosis is a term met by beginning biology students well before they reach college. A dictionary definition includes, "the living together in more or less intimate association or even close union of two dissimilar organisms."' There are two classes of symbiotes-ectosymbiotes and endosymbiotes. Ectosymbiosis is a less controversial topic because the partners are fairly easily separable and ide...

but on light for its life, and even the lightest clothing constitutes an artificial barrier between the body and the sun, that great source of life and energy. The practice of sun cure is as old as the earth, and a common saying is that ' There is nothing new under the sun Experimental contributions.?The remarkable successes of isolation in cases of surgical tuberculosis at high altitudes have ...

The launch of first-generation protease inhibitors (PIs) was a major step forward in HCV treatment. However, this major advance was restricted to genotype 1 (GT-1) patients. This year the launch of Sofosbuvir a NS5B nucleotide inhibitor (Nis), Daclatasvir a NS5A inhibitor (NS5A.I) and Simeprevir a second wave PIs open new perspective for IFN-free regimen. Both Sofosbuvir and Daclatasvir have a ...