a box-behnken design with three replicates was used for preparation and evaluation of eudragit vancomycin (vcm) nanoparticles prepared by double emulsion. the purpose of this work was to optimize vcm nanoparticles to improve the physicochemical properties. nanoparticles were formed by using w1/o/w2 double-emulsion solvent evaporation method using eudragit rs as a retardant material. full factor...

a rhamnolipid–type biosurfactant production by pseudomonas aeruginosa mm1011 was studied in a miniaturized shaken bioreactor. the operational parameters, affecting the biosurfactant production in shaken bioreactors, such as shaking frequency (200, 250, 300 rpm), filling volume (50, 75, 100 ml), and aeration rate (0.2, 0.6, 1 vvm), were optimized using response surface methodology. the optimizat...

environmental pollution by 2,4-dicholorphenol (2,4-dcp), commonly found in industrial wastewater has been a concern for humans over the past 50 years. garden radish peroxidase (grp) can eliminate this poisonous pollutant. the aim of this study was to apply an experimental response surface methodology (rsm) and central composite design (ccd) to optimize grp-based treatment in order to maximize ...

in this study fullerene functionalized using oleum (h2so4·so3), followed by the hydrolysis of the intermediate cyclosulfated fullerene as well as  an oxidizing agent was employed to functionalize the fullerenes. ruthenium was then added by the impregnation method or deposited on the functionalized fullerene. subsequent to this step, response surface methodology (rsm) was used to study the cumul...

in this work, hydrochloric acid is used to remove iron impurities in the bauxite ore contained in the diasporite mineral located in the sari region. the bauxite ore was calcined at different temperatures and times, and then dissolved in a hydrochloric acid solution. after determining the optimum calcination conditions in 1 h at 900 °c, the response surface methodology (rsm) with four factors in...

In this paper, the electric-discharge machining (EDM) of non-contact seal grooves was studied. Two types of material, namely: tungsten carbide and silicon carbide were tested by EDM due to their hard machining behaviors. The geometry of seal grooves is another reason why grinding or other precision machining processes cannot be applied. Four parameters of EDM processes were studied, namely: ele...

Modernization of mechanical industry has lead to the increase in demand for hard and tough materials and thus various non traditional methods have been developed in order to machine such hard and tough materials. Wire Electric discharge machine is one of the most commonly used machine which is employed in machining of conductive metals of any hardness or that are difficult or impossible to cut ...

In this study, a multi objective optimization for end milling of Al 6061 alloy has been presented to provide better surface quality and higher Material Removal Rate (MRR). The input parameters considered for the analysis are spindle speed, depth of cut and feed. The experiments were planned as per Taguchis design of experiment, with L27 orthogonal array. The Grey Relational Analysis (GRA) has b...

This study aims to create an image processing algorithm that categorises the wire electric discharge machine (WEDM) processed finish cut surfaces, based on surface microdefects. The also detects defect locations and suggests alternate parameter settings for improving integrity. proposed automated analysis is more precise, efficient repeatable compared manual inspection. Also, method can be used...