produced in man by inoculation of cultures of Leishmania tropica. Cutaneous inoculation of Leishmania donovani from spleen puncture material from a case of kala-azar, however, is reported to have ' apparently produced kala-azar in a man' but on two occasions accidental inoculation of spleen puncture material from cases of kala-azar was without any effect (Napier, 1927). Recently, Terry et al. (...

The immunomodulatory properties of lipophosphoglycans (LPG) from New World species of Leishmania have been assessed in Leishmania infantum and Leishmania braziliensis, the causative agents of visceral and cutaneous leishmaniasis, respectively. This glycoconjugate is highly polymorphic among species with variation in sugars that branch off the conserved Gal(β1,4)Man(α1)-PO4 backbone of repeat un...

background : the goal of this study was to know the identity of leishmania species responsible of cutaneous leishmaniasis (cl) in fars province, southern iran. methods : five counties of shiraz, firouz abad, ghir-karzin, farashband and larestan were pros-pected. forty-four patients exhibiting cutaneous lesions were selected. samples collected on skin le-sions were examined both microscopically ...

Leishmaniasis is a widespread arthropod-borne protozoan zoonosis caused by more than 21 Leishmania species. Vectors are sandflies of different genera. The disease is classified into "Old World" versus "New World" leishmaniasis and further subclassified in cutaneous, mucocutaneous and visceral forms. Most therapeutic approaches are not evidence-based. We report a patient with facial cutaneous Le...

this study investigated the in vitro production of interferon-γ, interleukin (il)-10, il-12, and il-13, after antigenic stimulation of the cells (with leishmania antigen and lipopolysaccharide) using whole blood from patients with cutaneous leishmaniasis lesions caused by leishmania tropica and in volunteers with history of cutaneous leishmaniasis. elisa results showed that the mean production ...

Leishmaniasis is common in western and southern portions of Venezuela, where it tends to occur in hot, humid regions below 600 meters. This article describes the results of a survey pe$ormed during 1978-1979 in westem Venzzuela above 600 meters, where teishmaniasis caused by a recentb iaknt$ed parusitz (Leishmania gamhami) is common, but where the mucosal lesions often associated with the disea...

Cutaneous leishmaniasis is an infectious disease that is caused by protozoa belonging to the genus Leishmania and typically manifests with a single lesion on sun exposed areas. It is frequent in the Mediterranean Basin where it is most commonly due to Leishmania Infantum. In the literature, there is a number of reports describing atypical presentations, including that manifesting with multiple ...

Whether cutaneous leishmaniasis exists in China is a problem of concern in the international field of parasitology. Zhang and Hu (1983) found a girl aged 15 with mild hepatomegaly and cutaneous ulcer on her right cheek in Shawan County of Xinj­ iang; Leishmania was detected in both the exudates and biopsy tissues, but the parasite was not detected in a bone marrow smear. Notwithstanding the fac...

An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana. In an attempt to pinpoint alterations in the signaling pathways responsible for the NK-cell dysfunction in patients with DCL, this study aimed at identifying differences in the NK-cell response towa...

A case of HIV/Leishmania co-infection presenting both visceral and cutaneous manifestations is reported. Leishmania infection was confirmed by conventional methods (parasitological approach and serology) and by PCR. Leishmania chagasi isolated from the skin lesion was characterized by enzyme electrophoresis and by restriction fragment length polymorphism of the internal transcribed spacer of th...