The isolation and characterization of a human T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is described. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia b...

HTLV-I is a retrovirus now identified as the etiologic agent of two diverse disease processes: ATLL, an aggressive T-cell malignancy; and TSP/HAM, a chronic progressive myelopathy. Transmission can occur horizontally through blood transfusions, IV drug abuse and sexual intercourse. Vertical transmission may also occur. Available diagnostic modalities are serologic in nature and include the EIA ...

Background & Aims: Dry type localized cutaneous Leishmaniasis due to Leishmania tropica is one of the most prevalent cutaneous parasitic infections in Kerman province. It seems that cellular immune response and the nature of immune inflammatory cells comprising the inflammatory background play a determinant role in this infection. Methods: Skin biopsies of 53 patients with acute(<2 years durati...

Human T-ceil lymphotropic virus, type 1 (HTL V-I) is considered to be the causative agent of adult T-cell lymphoma/leukemia and spastic paralysis, and seems to be common in Khorasan Province. 300 blood samples from Mashhadi and 180 from Gonbadi blood donors were obtained (all samples from healthy subjects). Serological screening was done by passive particJe- agglutination test and confirme...

human t-ceil lymphotropic virus, type 1 (htl v-i) is considered to be the causative agent of adult t-cell lymphoma/leukemia and spastic paralysis, and seems to be common in khorasan province. 300 blood samples from mashhadi and 180 from gonbadi blood donors were obtained (all samples from healthy subjects). serological screening was done by passive particje- agglutination test and confirmed by ...

OBJECTIVE(S) Lichen Planus is a common disease with unknown etiology which affects the skin and mucosa. Recent studies have focused on the possible role of the virus in the pathogenesis of Lichen Planus. The purpose of this study was to determine the association between the human T-cell lymphotropic virus type 1 and Lichen Planus. MATERIALS AND METHODS This case control study was conducted on...

Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Only a limited percentage of infected individuals develop disease in response to the virus while the majority remain asymptomatic and HAM/TSP is the most common clinical manifestation of the virus. HAM/TSP is an inflamma...

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