background and aims. incorporation of nano-particles to orthodontic bonding systems has been considered to prevent enamel demineralization around appliances. this study investigated cytotoxicity of transbond xt adhesive containing 1 wt% titanium dioxide (tio2) nano-particles. materials and methods. ten composite disks were prepared from each of the conventional and tio2-containg composites and ...

nowadays, growing interest in the application of nanotechnology in biomedical and biotechnological fields has opened a new avenue to explore the nanoparticles-biological system interaction. indeed, a clear gap is still in the cytotoxic effect of nps on the biological systems. for this purpose, the interaction of the silica oxide nanoparticles (sio2-np) with pc12 cell line, as a model of nervous...

in the present work, the bioassay screening of the essential oil and various extracts of two plants including fruits of heracleum persicum desf. and rhizomes of zingiber officinale rosc. have been studied with brine shrimp test. there is only one report about cytotoxicity of h. sphondylium in literature and so h. persicum has been used as second selection. at first essentials oil and various ex...

brown alga, turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). the extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. minimal inhibitory concentration was determined for active extracts by broth dilution method. the antiviral activity and cytotoxicity of the extracts were tested in human embryon...

objective(s):berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. but the effect of berberine on breast cancer has not yet been completely studied. in this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. materials and methods: the antiproliferative effects of berberine and doxorubicin alone and in c...

objective(s) the aim of the present study was to compare the therapeutic indices of several agents used in treatment of inflammatory conditions which included: vitamin e, hydro-alcoholic extracts of glycyrrhiza glabra, matricaria aurea, dexamethasone, piroxicam and diclofenac using wehi-164 fibrosarcoma cells. materials and methods cytotoxicity evaluation was based on vital dye exclusion assay....

lactic acid bacteria which are  used  as  probiotics  have  ability to  modulate  immune responses and modify immune mechanisms. it has also been indicated that some strains of this family can affect the immune responses against solid tumors. in the present work, we proposed to study the effects of oral administration of l.cacesi ssp casei on the nk cells cytotoxicity and also production of cyt...

the essential oil from the aerial parts ofjurinea leptoloba dc., collected from shiraz (south of iran), was investigated for total phenolic content (tpc), antioxidant and cytotoxic effects. tpc of j. leptoloba oil was determined to be 16.53 ± 5.69 μg gallic acid equivalent/mg sample (μg gae/mg oil) using the folin-ciocalteau assay. the ferric reducing power of the oil was determined 0.117 ± 0.0...

nanomaterials (nms) are widely used in health and biomedical applications, however, only a few studies investigate their toxic effects.  the present report signifies a contribution to the study of the toxic effects of silver nanoparticles (ag nps)  on   e. coli cells, which is a model organism of anthropogenic pollution. the toxicity of nanoparticles depends on their  chemical and surface prope...

background: the anti-cancer effects of honey bee venom (bv) and chrysin might open a new window for treatment of chemo-resistant cancers. this study was designed to evaluate cytotoxic and pro-apoptotic effects of bv and chrysin on a2780cp cistplatin- resistant human ovarian cancer cells. methods: as per the study objectives, a2780cp cells were categorized to 4 groups: 3 experiment groups (treat...