extracts derived from viscum album have been shown to kill cancer cells in vitro. some studies have noted that different species of this plant collected from around the world displayed cytotoxic effects in different extents. in the present study, we evaluated the effects of iranian mistletoe extracts on five cancer cell lines. plants growing on hornbeam tree (carpinus betulus) were collected, a...

safety and beneficence of farm animal nutrition plays a great role in their healthy life which in turn have impact on human nutrition via diary or meat products. assessing safety and beneficence of vicia varibilis freyn and sint. which is chosen intrinsically by domesticated animals of kohgiluyehand boyerahmad iranis the aim of the present work. our results not only show no cytotoxic activity i...

objective(s) the cytotoxic effects of crude ethanol extracts of some previously tested iranian conifers  on tumor cell lines have motivated us to screen different parts of two subspecies in these genus. materials and methods terminal branchlets and berries of juniperus excelsa subsp. excelsa and j. excelsa subsp. polycarpos were collected, dried and extracted with ethanol/h2o (80/20 v/v) via pe...

background: the extensive use of different nanoparticles has raised great concerns about their occupational and biological safety. objective: the aim of this study was to evaluate the cytotoxic effect of zinc oxide nanoparticles (zno nps) on viability of spermatozoa. materials and methods: semen samples were obtained from 15 healthy persons, and were analyzed using who guidelines. each semen sa...

background: during the past few years, hesa-a, a herbal-marine mixture, has been used to treat cancer as an alternative medicine in iran. however, weight of the evidence is not sufficient to accept or refuse the use of this compound as a cytotoxic drug. we investigated the selective anticancer effects of hesa-a on breast, prostate, colon, and glioblastoma multiforme (gbm) neoplastic cell lines....

clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. it has been proved to be a causative agent in antibiotic-associated diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. this study was aimed to determine the prevalence of c.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. the 942 hospitalized patie...

introduction: root canal disinfection is an important step in regenerative endodontic treatments. an ideal irrigating solution must have high antimicrobial activity and minimum cytotoxicity. this study sought to assess the effect of some irrigating solutions on stem cells from the human apical papilla (scap) after different periods of exposure. methods and materials: stem cells were isolated fr...

the chloroform soluble fractions of ethanolic extracts of five inula belonging to the compositae family were evaluated for cytotoxic activity against five different cell lines including caco2 (human colon adenocarcinoma), mcf7 (human breast adenocarcinoma), hepg2 (human hepatocellular carcinoma), vero (green african monkey kidney) and wehi164 (balb c mouse fibrosarcoma). cytotoxicity was assess...

the biological application of nanoparticles (nps) is a rapidly developing area of nanotechnology that raises new possibilities in the treatment of human cancers. the cytotoxicity was evaluated by mtt and ldh assays. the apoptotic effect of free icd-85 and icd-85 nps on hela cells was assessed using caspase-8 colorimetric assay. the mtt assay showed that icd-85 nps could enhance the in-vitro cyt...