When working together, people engage in non-contractual and informal interactions that constitute the sociology of the group. We use behavioral models and a unique survey of medical groups to analyze how group sociology influences physician incentive pay and behavior. We conclude that informal interactions among group members influence pay practices and behaviors, but the relationship is comple...

BACKGROUND Chronic anemia is a well-recognized complication of both cancer and cytotoxic treatments and is associated with symptoms (e.g., fatigue, dyspnea) that may induce or exacerbate functional deterioration. The use of recombinant human erythropoetin (rHuEPO epoetin alfa) clearly increased haemoglobin (Hb) levels, decreased transfusion needs and allowed recovery of quality of life in anemi...

Background A multipeptide vaccine containing 6 melanoma-associated peptides to stimulate helper T cells (6MHP) is safe and immunogenic has clinical activity. phase I/II trial was designed evaluate safety immunogenicity of 6MHP vaccines plus PD1 blockade. Methods Participants with measurable advanced melanoma, age ≥ 18 years, ECOG performance status 0–1 were administered intradermally subcutaneo...

T his paper investigates the heterogeneous reaction of Iranian exporters to the tariff rate changes, how export prices are influenced differently by the increase or decrease in foreign importers’ tariff rate. Using the Iranian transaction level export data and firm level data during the period 2002-2015, we find that tariff pass through for Iranian firms are incomplete and exporters ...

Background Treatment for relapsed/refractory [r/r] AML and high risk MDS is dismal NK cell infusions (with IL-2 or IL-15) after lymphodepleting chemotherapy can result in 30–40% remission. However, cells lack antigen specificity require cytokine expansion. We have developed a novel tri-specific molecule, 1 termed GTB-3550 TriKE, comprised of IL-15 surrounded by two single chain variable fragmen...

Introduction: Despite aggressive surgery, radiotherapy and chemotherapy, malignant gliomas remain fatal. As these tumors are highly angiogenic, therapies directed against tumor vasculature or preventing angiogenesis have been developed. Monitoring changes in structural and functional microvasculature should help to evaluate the efficiency of these therapies. Previous results suggest that MRI fo...

This study aimed to investigate the diagnostic performance of trace apparent diffusion coefficient (tADC) maps in prostate cancer (PCA) detection at different spatial resolutions and number of averages (NAV), and to determine a practical protocol that could provide satisfactory diagnostic performance for PCA detection. The tADC maps were reconstructed into three different isotropic resolutions,...

Introduction: CD19 is an established target of multiple B-cell lymphoma therapies. Blockade CD47, a macrophage immune checkpoint inhibitory ligand, induces tumor-cell phagocytosis. TG-1801 CD19/CD47 bispecific antibody designed to selectively block CD47 on CD19+ cells, while retaining functional IgG1 Fc domain. Herein we report updated results from the FIH study. Methods: The primary objectives...

E nergy is one of the main and essential factors in economic growth. Electricity as one of the most important resources of energy supply for economic sectors on one hand, and as an index of welfare, on the other hand, is one of the economic development benchmarks. The growth of GDP will increase the demand for energy resources, including electricity. Hence, policymakers should pay at...

A body of literature suggests that ethnic heterogeneity limits economic growth. This paper provides microeconometric evidence on the direct effect of ethnic divisions on productivity. In team production at a plant in Kenya, an upstream worker supplies and distributes flowers to two downstream workers who assemble them into bunches. The plant uses an essentially random rotation process to assign...