background: in an effort to understand what limits the virulence of malaria para­sites in relation to the host genetic and immunogenic background, we investi­gated the possibility that the parasite and host genotype crossover interac­tions constrain virulence. methods: two groups of mice from different genotypes were used (c57bl/6 (b6) and dba/2 mice). the mice were infected with a virulent par...

background: methamphetamine (ma) is one of most common illicit drugs which were reported that nearly half of ma consumers are women. ma can cross through placenta and affects pregnancy and fetus development. objective: our aim was to evaluate effects of injected ma on crown-rump length, head and placental circumference, body weight, histological changes and apoptosis in fetus. materials and met...

introduction: regarding chronic nature of epilepsy and its side effects and to access the effective treatment procedures, herbal medicine has received remarkable interest. the aim of this study was to determine the anticonvulsant effects of hydro-alcoholic extract of anethum graveolens seed on pentylenetetrazol (ptz) -induced seizure in male mice. methods: fifty-six albino male mice were divide...

introduction: tanacetum sonbolii (asteraceae) is an endemic species in iran. in the present study, we examined the effects of tanacetum sonbolii hydroalcoholic extract on the formalin test in mice. methods: 126 swiss albino mice weighing 230-280g were used as subjects. the formalin test was performed on two control groups (marked as intact and saline groups n = 6 in each group) and an experimen...

background: catsper genes are a novel family of four sperm-specific calcium channels, which indicate testis-specific expression patterns. despite the crucial role of catsper genes in the male reproduction, very little is known about the factors that regulate their expression. objective: the objective of this study was to investigate the effects of vitamin e treatment on the expression of catspe...

conclusions based on its effects, carnosol might be considered a source of drug, showing effective immunosuppression properties. further studies should be performed on carnosol to develop an effective immunosuppressive drug or coadjuvant for the treatment of disorders caused by an exaggerated or unwanted immune response. results results showed that three high doses of carnosol (0.8, 2.4 and 4 m...

the susceptibility of various strains of mice to infection by leishmania tropica (major) was recently studied in this laboratory. the infection in a/j, c3h, cba, akr/j, akr/cu, and c57b1 mice (the semi resistant strains) remained cutaneous and the animals recovered within 4-6 months. however balb/c mice developed generalized infection after two months of exposure resulting in death 3-4 months l...

This contribution contains 3D models of upper molar rows house mice (Mus musculus domesticus). The erupted parts the right row and first are presented for specimens belonging to four groups: wild-trapped mice, wild-derived lab offspring, a typical laboratory strain (Swiss) hybrids between Swiss mice. These analyzed in following publication: Savriama et al 2021: Wild versus mice: Effects age, di...

mancozeb, a fungicide of a manganese-zinc ethylenebisdithio-carbamate (ebdc), was administered by gavage at doses of 200, 400, 600 and 800 mg/kg/day to female virgin mice for 30 days. the mice were autopsied on 31st day. mice were also treated with similar doses for a period of 30 days and the treatment was withdrawn for a further period of 30 days for reversible study. the mice were autopsied ...

background: the present study deals with the effect of helminthic infection as nematode parasite like aspiculuris tetraptera on the haematological parameters of infected and vaccinated mice. methods: totally 15 mice were used. five mice were used for positive control, 5 mice used for nega­tive control and 5 mice used for experiment. the hematological parameters were studied viz. rbc, hb, and se...