We examined the ability of nitric oxide (NO) to stimulate the ADP-ribosylation of proteins from the mouse macrophage cell line ANA-1. To demonstrate a specific effect of NO, we used a novel compound named diethylamine dinitric oxide (DEA/NO; 1,1-diethyl-2-hydroxy-2-nitrosohydrazine, sodium salt; [Et2NN(O)NO]Na), which releases NO in aqueous solution at neutral pH. DEA/NO stimulated the ADP-ribo...

Data envelopment analysis (DEA) is a method for measuring the efficiency of peer decision making units (DMUs). Recently network DEA models been developed to examine the efficiency of DMUs with internal structures. The internal network structures range from a simple two-stage process to a complex system where multiple divisions are linked together with intermediate measures. In general, there ar...

In recent years, much governmental investment has been committed to R&D in the area of information technology industry. However, its commercialization rate is reported to be lower than expected. In order to prevent such waste, feedback information obtained from the rigorous evaluation of the finished R&D project needs to be utilized for future selection of new projects. The main purpose of our ...

Amiodarone (AMD)-induced pulmonary toxicity (AIPT) is the most life-threatening side-effect of AMD treatment. N-Monodesethylamiodarone (DEA), an active metabolite of AMD, also exhibits cytotoxicity and tends to accumulate in the lung more intensively than AMD. In this study, we characterized the mechanism of DEA accumulation using A549 cells as a model of the alveolar epithelium. Typical ATP-de...

In this paper, we discuss the relationship between multi-attribute utility theory and DEA models without explicit inputs (DEA-WEI), including dual models and some theoretical analysis of DEA-WEI models. We then propose generic DEA-WEI models with quadratic utility terms. Finally, we provide illustrative examples to show that DEA-WEI with suitable quadratic utility terms are able to reflect some...

Based on the R&D activities of Shanghai’s high-tech industries during 2010 to 2012, this paper uses super efficiency DEA model to analyze and evaluate the R&D efficiency of Shanghai’s hightech industries. The results show that the R&D efficiency of Shanghai’s high-tech industries has dissimilitude. The R&D efficiency values of some high-tech industries are relatively low. There are many redunda...

This paper studies the effects of heteroscedasticity on the following five types of estimators: (1) Data Envelopment Analysis (DEA) per se as well as DEA joined to regression forms, (2) Corrected Ordinary Least Squares based on maximum residual (COLS-R), (3) Corrected Ordinary Least Squares based on moments of residuals (COLS-M), (4) Maximum Likelihood Estimation (MLE), and (5) Goal Programming...

data envelopment analysis (dea) is a technique used to compare efficiency in various sectors such as hospitals, chain stores, and dealerships. it represents a set of linear programming techniques and uses deter-ministic data (inputs and outputs), in stable conditions. the dea technique cannot be used when there is data with indeterministic nature, or when there is an environment with dynamic co...