abstract background beta-thalassemia is a common hereditary hemoglobinopathy, which is a reason of microcytic hypochromic anemia. patients with major thalassemia require multiple blood transfusions. this study evaluated growth in thalassemic patient and relationship with ferritin level. materials and methods this is a cross sectional study on seventy patients (36 boys, 34girls) with transfusion...

background: thalassemia is a series of hemoglobinopathies in which the production of perfect hemoglobin is completely or partially suppressed. using injectable iron chelators have been dominating treatment for the iron overload caused by recurrent blood transfusions in thalassemic patients, however, a new oral iron chelating drug (exjade) have been recently introduced and might be cost effectiv...

Background: Thalassemia is a series of hemoglobinopathies in which the production of perfect hemoglobin is completely or partially suppressed. Using injectable iron chelators have been dominating treatment for the iron overload caused by recurrent blood transfusions in thalassemic patients, however, a new oral iron chelating drug (Exjade) have been recently introduced and might be cost effec...

Acute Ischemic Syndromes To the Editor: Congratulations to Duffy et al1 on their well-written article, “Iron Chelation Improves Endothelial Function in Patients With Coronary Disease.” We completely agree that increased body iron stores may be a risk factor for atherosclerosis and may accelerate endothelial dysfunction in acute ischemic syndromes. Hence, deferoxamine, an iron chelator, should p...

Aeromonas infection in humans is associated with certain underlying diseases, especially chronic liver disease or malignancy. However, Aeromonas infection associated with iron overload is rarely reported. We report a case of a 47-year-old female with end-stage renal disease on haemodialysis and on deferoxamine treatment for iron overload who developed Aeromonas sepsis with septic embolism and r...

Using a spectrometer with an argon plasma source coupled to a high-frequency magnetic field, we developed a direct method for determining iron in urine of patients being treated with deferoxamine. The detection limit for iron was 75 nmol/L; added iron was satisfactorily recovered; and we observed no interference from deferoxamine at its most commonly used concentrations. Values for between-run ...