Streptococcus mutans present in a man on a world wide basis (Birgitta Kohler & Douglas Bratthall 1976). High numbers in the mouth of Streptococcus mutans are associated with both high prevalence and a high incidence of dental caries. The Directorate of Oral Health Ministry of Health Republic of Indonesia declared 60 80 percent of school children between 4 14 years by age were suffering from den...

OBJECTIVES This study investigated the relationship between urease and arginine deiminase system (ADS) activities and dental caries through a cross-sectional study. MATERIAL AND METHODS Urease and ADS activities were measured in saliva and plaque samples from 10 caries-free subjects and 13 caries-active. Urease activity was obtained from the ammonia produced by incubation of plaque and saliva...

5 Dental caries is frequently defined as a “multifactorial disease” on the grounds that its onset involves carbohydrates, oral microorganisms, acids, salivary flow, fluoride, and the frequency of carbohydrates intake. However, there is extensive scientific evidence that free sugars are the primary necessary factor in the development of dental caries. After sugar consumption there is an increase...

The association of Streptococcus mutans with human dental decay was investigated by using several types of samples: (i) paraffin-stimulated saliva samples taken from children with from 0 to 15 decayed teeth; (ii) pooled occlusal and approximal plaque taken from children with no decayed or filled teeth, or from children with rampant caries of 10 or more teeth; (iii) plaque removed from single oc...

PURPOSE Cystic fibrosis (CF) is one of the most common genetic diseases worldwide. It is caused by mutations of the gene situated on the long-arm of the 7th chromosome coding Cystic Fibrosis Transmembrane Conductance Regulator (CFTCR) which is responsible for the synthesis of cAMP-dependent membrane chloride channel located on the top surface of epithelial cells of exocrine glands. Accumulation...

BACKGROUND The non-communicable diseases dental caries and periodontal diseases pose an enormous burden on mankind. The dental biofilm is a major biological determinant common to the development of both diseases, and they share common risk factors and social determinants, important for their prevention and control. The remit of this working group was to review the current state of knowledge on ...

BACKGROUND The genotypic diversity and cariogenicity of C. albicans from the dental plaque of children are poorly understood. This study aimed to explore the genotypic diversity and cariogenicity of C. albicans from children with early childhood caries and caries-free children. METHODS Dental plaque samples from 238 children with early childhood caries and from 125 caries-free children were c...

Dental caries is caused by a combination of infection and diet. This disease, if left untreated, may lead to pain, and impair the quality of life, nutritional status and development of young children. The objective was to investigate the association between snacking and caries in a population at high risk of dental caries. American preschool children (n = 1,206) were recruited in the offices of...

Dental caries is a well known major oral health problem in most countries. The multifactorial etiology of the disease includes multiple bacterial species, S. mutans is the main pathogen associated with the disease. Streptococcus mutans is recognized as the main pathogen of dental caries in human beings. One of the important virulence properties of S. mutans is their ability to form biofi lms on...

Research has demonstrated the validation of specific caries risk assessment (CRA) systems, but little is known about how dental practitioners assign a caries risk level to their patients. The aim of this study was to explore dental students' decision making in caries risk assignment when using the Caries Management By Risk Assessment (CAMBRA) system. Multiple correspondence analysis and chi-squ...