background exposure to morphine decreases neurogenesis in the hippocampus. recent studies have shown that voluntary running decreases the severity of anxiety behaviors and cognitive deficits, and increased synaptic plasticity in morphine-dependent rats. objectives this study aimed to investigate whether the morphine dependence-induced attenuation of hippocampal neuron number in rats would be re...

post-traumatic stress disorder (ptsd) is a syndrome causing from a severe traumatic happening that leads to threatened death or injury. ptsd is associated with changes in limbic, hippocampal, and prefrontal cortical region function due to changes in synaptogenesis, dendritic modifying, and neurogenesis. changes in neuron in ptsd patients result from pathophysiological disturbances in inflammato...

preparations of platelet concentrates (pcs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (pmps) with high coagulant activity that may change platelet efficacy and safety issues. high shear stress could cause shedding of pmps from the platelet plasma membrane, platelet aggregation, and activation of the co...

The expression of members of the platelet-derived growth factor (PDGF) system in bone marrow cells derived from Idiopathic myelofibrosis (IMF) has been investigated by real-time RT-PCR. Increased expression of PDGFs and the corresponding PDGF receptor a could be demonstrated to be a feature of advanced fibrosis in IMF that is not demonstrable in the prefibrotic phase of the disease.

background :cell-based therapies can be used to treat neurological diseases and spinal cord injuries. the aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (bm-mncs) transplantation in patients with spinal cord injuries.   method s: following a systematic review to detect clinical intervention studies, a meta-analysis was done for pooling data to esti...

objective(s): the present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. materials and methods: oxaliplatin (5 mg/kg) or saline was administered to adult male sprague-dawley rats.  gabapentin (60 mg/kg, ip) or vehicle was injected daily. mechanical allodynia was assessed us...

background and aims. plasma rich in growth factors (prgf) is a concentrated suspension of growth factors, which is used to promote periodontal tissue regeneration. the aim of this randomized, controlled, clinical trial was to evaluate of the treatment of grade ii mandibular molar furcation involvement using autogenous bone graft with and without prgf. materials and methods. in this double-blind...

We present microparticle image velocimetry measurements of suspended microparticles of diameters from 0.6 to 10 μm undergoing acoustophoresis in an ultrasound symmetry plane in a microchannel. The motion of the smallest particles is dominated by the Stokes drag from the induced acoustic streaming flow, while the motion of the largest particles is dominated by the acoustic radiation force. For a...

A funder is incorrectly omitted from the Funding statement. The correct Funding statement is as follows: This work was supported by a Polish-German cooperation grant (S007/P-N/2007/01); National Science Center grant N N401 324739; EMBO Short-Term Fellowship to E. Z. (ASTF 211.00.2007); GA No 264173 (Bio-Imagine) and statutory funds for the Nencki Institute. The funders had no role in study desi...