the effect of onion and garlic extracts on fungal growth and keratinolytic activity was studied in trichophyton mentagrophytes as one of the major etiologic agents of human and animal dermatophytosis in iran and other parts of the world. in order to find out the best keratinase producer for further steps, culture conditions for 30 strains of t. mentagrophytes isolated from human dermatophytosis...

The efficacy of ketoconazole was evaluated in twenty patients with chronic dermatophyte infections who had failed to clear with griseofulvin therapy. Trichophyton rubrum was the causative organism in nineteen of the patients, and Trichophyton mentagrophytes in one patient. Three of twelve organisms tested showed in vitro resistance to griseofulvin. Duration of infection ranged from 2 to 28 year...

the purpose of this study was to determine the therapeutic efficacy of citric and tartaric acids on experimental dermatophytosis in guinea pigs. in this study, the susceptibility of trichophyton mentagrophytes var. mentagrophytes to citric and tartaric acids was assessed using the macrodilution broth method. in the animal experiments, a cream consisting of the mixed acids was topically applied ...

physiological mediators of human host such as androgenic hormones interfere pathogenic fungal growth. it has been revealed that the growth of yeasts as well as of dermatophytes is influenced by human androgenic hormones in vitro. in this reason for in vivo condition, the andrgenic hormones level must be measured in patients with dermatophytosis and healthy individuals. to this purpose we measur...

Dermatophytoses form over 16–75% of all the mycological infections. It is more prevalent in tropical and subtropical countries including India, where heat and moisture play an important role. 1 Although not life threatening, its severity can cause great discomfort particularly in immunosuppressive conditions. It remains a general public health problem, which is prevalent in all age groups and b...

Most fungal infections of the cornea are secondary infections, caused by opportunis­ tic fungi that have invaded a diseased cornea or one that has been treated with corticosteroids or broad-spectrum antibiotics. Two ex­ ceptions are corneal infections due to Can­ dida albicans or Aspergillus species; these may infect an apparently normal cornea af­ ter minimal trauma. Superficial mycotic infect...

background: in the present study, a pcr-rflp based molecular technique was designed to rapid identification of der­matophytes in clinical specimens. skin scrapings obtained from human cases suspected to dermatophytosis were studied in or­der to identify involved etiological fungi. methods: in this experimental study, the specimens (skin scrapings) of patients referred to mycology department of ...

objective: dermatophytosis is one of the most common pandemic fungal infections that is a major health problem in cities and villages. this study aims to evaluate pcr sensitivity and accuracy in the detection of nail dermatophytosis compared to conventional direct and culture detection methods, and performs an assessment of trichophyton rubrum in patients suspected of having nail dermatophytosi...