AIM To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. METHOD A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification programme. RESULTS 83 patients were seen before detoxification (mean age 27.1 (SD 4.6) years) and 69 after detoxification. The horizontal angle o...

BACKGROUND To date there has been limited research on both the prevalence of overdose and drug user knowledge about overdose prevention and response methods in China. In addition, there has been no effort to integrate naloxone information and distribution into pre-release services for drug users detained in isolated compulsory detoxification facilities in China. METHODS The authors conducted ...

Long-term metal exposure risk assessment for aquatic organism is a challenge because the chronic toxicity of chemical is not only determined by the amount of accumulated chemical but also affected by the ability of biological regulation or detoxification of biota. We quantified the arsenic (As) detoxification ability of tilapia and developed a biologically based growth toxicity modeling algorit...

Introduction: The fate of xenobiotics that is present, increasing day by day. The increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. Methods: The present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by Panax ginse...

Two strategies leading to enzyme saving during saccharification of pretreated lignocellulo-starch biomass (LCSB) was investigated which included reducing enzyme dosage by varying their levels in enzyme cocktails and enhancing the fermentable sugar yield in enzyme-reduced systems using detoxification chemicals. Time course release of reducing sugars (RS) during 24-120 h was significantly higher ...

organophosphorus compounds are highly toxic chemicals that have application in production of warfare agents and agricultural pesticides. detoxification of areas that have been exposed to these types of materials is of vital importance and several approaches have been used for this purpose. biodegradation of organophosphates is one of these approaches that is in the center of attention due to it...

background: a number of drugs are used to control opioid withdrawal symptoms during detoxification. tramadol, as a partial opioid agonist, has been widely used to manage acute and chronic pains. the present study was designed to assess the effectiveness of tramadol in methadone-assisted detoxification.   methods: in a double-blind randomized clinical trial 72 opioid-dependent patients as define...