نتایج جستجو برای: detoxification
تعداد نتایج: 9839 فیلتر نتایج به سال:
Methylated forms of arsenic (As), monomethylarsenate (MMA), and dimethylarsenate (DMA) have historically been used as herbicides and pesticides. Because of their large application to agriculture fields and the toxicity of MMA and DMA, the persistency of these compounds in the environment is of great concern. MMA and DMA sorption and desorption were investigated in soils, varying in mineralogica...
This work demonstrates an alternative method to prepare allylated arenes and aryl-substituted allylic esters via catalytic decarboxylative C-C bond formation using aromatic carboxylic acids and allylic halides and esters.
Nickel hydrides supported by a terphenyl diphosphine were synthesized and found to undergo nickel-to-arene H-transfers. Some of the resulting complexes also undergo the reverse (C-to-Ni) H-migration, indicating the potential for storing H-equivalents in this type of pincer ligand. NMR spectroscopy, single crystal X-ray diffraction, and isotopic labeling studies investigating the mechanism of th...
DETOXIFICATION: A GENERAL OVERVIEW James L. Wilson D.C., N.D., Ph.D. From the late 1800s until recently, the value and use of detoxification have been championed mainly by the naturopathic profession and those interested in natural health. However, with the emergence of increasingly sophisticated laboratory tests and the growing influence of natural medicine, detoxification is gaining recogniti...
BACKGROUND Vancouver, Canada recently opened a medically supervised injecting facility (SIF) where injection drug users (IDU) can inject pre-obtained illicit drugs. Critics suggest that the facility does not help IDU to reduce their drug use. METHODS We conducted retrospective and prospective database linkages with residential detoxification facilities and used generalized estimating equation...
BACKGROUND The purpose of this case series was to review the management of burn patients who requested ultrarapid opioid detoxification under anesthesia after extended duration of narcotic use for chronic pain related to burn injury. METHODS The treatment plan of six opioid-dependent burn patients was analyzed to assess the effectiveness of our detoxification practice to date. Demographic and...
In model studies towards the synthesis of harringtonolide, the construction of the tropone moiety via arene cyclopropanation was investigated. The installation of the lactone ring was accomplished by way of a Diels-Alder cycloaddition of various indenones and a-pyones. The incorporation of the key bridge methyl group and subsequent control of its stereochemistry is also outlined.
Adaptor proteins participate in selective autophagy, which is critical for cellular detoxification and stress relief. However, new evidence supports an autophagy-independent key role of the adaptor p62 (encoded by the gene Sqstm1) in signaling functions central to tumor initiation in the epithelium and suppression of tumor progression in the stroma.
A selective and practical bromine-metal exchange on bromoheterocyclics bearing substituents with an acidic proton under non-cryogenic conditions was developed by a simple modification of an existing protocol. Our protocol of using a combination of i-PrMgCl and n-BuLi has not only solved the problem of intermolecular quenching that often occurred when using alkyl lithium alone as the reagent for...
The Regional Superfund Ground Water Forum is a group of ground-water scientists, representing EPA's Regional Superfund Offices, organized to exchange up-to-date information related to ground-water remediation of Superfund sites. One of the major issues of concern to the Forum is the transport and fate of contaminants in soil and ground water as related to subsurface remediation. Processes which...
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