Diabetes mellitus is a composite disease and multiple factors are involved in its development. If not managed appropriately, acute and long-term complications may compromise the patient’s wellbeing and possibly result in death. While acute complications may be detected and addressed promptly, long-term complications are insidious and not easily recognisable by the patient. The medical practitio...

introduction: depression is one of the most prevalent mental disorders in patients with diabetes, which affects on cooperation in implementation of treatment measures, consequences of therapeutic and diabetes complications. is thought, low self-esteem is endangering balance of mental and emotional person and is caused development of depression. this study was performing with goal of comparison ...

Epidemic of diabetes, affecting about 3–5% of Western populations, is one of the main threats to human health in the 21st century (1). Changes in the human environment, behavior, and lifestyle have resulted in a dramatic increase in the incidence and prevalence of diabetes in people with genetic susceptibility to diabetes. The global number of people with diabetes was 151 million in 2000, and i...

1. Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993:329:977-86. 2. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and r...

Diabetes mellitus is a group of metabolism-related diseases characterized by elevated plasma glucose levels, and the course diabetes closely linked to development diabetes-related complications, which can be life-threatening due poor glycemic control. Exosomes are small vesicles that encapsulate intracellular molecules composed variety bioactive proteins, lipids nucleic acids (including microRN...