The CDM is a peer-reviewed, validated model, which employs standard Markov techniques to describe the long-term incidence and progression of diabetes-related complications. A complete description of the CORE Diabetes Model, including validations, can be found in the literature1,2. The cohort characteristics was based on the Opt2mise3 study for age, diabetes duration, gender proportion and HbA1c...

OBJECTIVE To estimate the incidence densities and cumulative incidence of diabetes-related complications in patients with type 1 diabetes for a maximum of 15-year follow-up. The estimations were further stratified by gender and age at diagnosis (ie, early onset: 0-12 years, late onset:≥13 years). DESIGN A population-based retrospective longitudinal cohort study. SETTING Taiwan's National He...

OBJECTIVES Diabetes requires continuous medical care including prevention of acute complications and risk reduction for long-term complications. Diabetic complications impose a substantial burden on public health and care delivery. We examined trends in regional differences in hospitalisations due to diabetes-related complications among the total diabetes population in Finland. RESEARCH DESIG...

Diabetes complications can be related to the long duration of disease or chronic hyperglycemia. The follow-up diabetic patients is based on control hyperglycemia, although this correction, if obtained rapidly in people living with severe paradoxically interfere even induce complications. We reviewed literature describing impact rapid and intense treatment hyperglycemia review showed that worsen...

The global prevalence of diabetes mellitus among adults has risen from 4.7% in 1980 to 8.5% in 2014, increasing the number of adults with diabetes mellitus to a staggering 422 million worldwide, according to the World Health Organization. For comparison, this number is larger than the total population of the United States. Diabetes mellitus not only reduces quality of life and life expectancy, ...

Respected on both sides of the Atlantic for questioning the tenets underlying the pathophysiology of diabetes and its complications, Trevor Orchard continues to influence the fields of epidemiology and medicine. With a self-effacing style that might be described as typically British, he remains provocative and prominent among the research community. An Englishman educated in Wales and living in...

BACKGROUND Diabetes is increasingly becoming a major chronic disease burden all over the world. This requires a shift in healthcare priorities and up-to-date data on the epidemiology and impact of diabetes in all regions of the world to help plan and prioritize health programs. We systematically reviewed the literature on diabetes prevalence and its complications in the UN sub region of Norther...