to achieve tight glycemic control in diabetic patients, it may be necessary to introduce insulin therapy much earlier in the disease course. poor glycemic control is a risk factor for the development of diabetic complications. many patients require insulin therapy after several years of disease in order to maintain good glycemic control and prevent complications. but many patients do not receiv...

background: among the non-communicable diseases, diabetes mellitus has an important ranking and with annually increasing rate where it is expected the number of people suffering from the disease will reach to 300 million up to 2025 in all of world. the prevalence of type 2 diabetes in iran is 4-4.5% and in population aged above 30 years is greater than 14%. the present study is attempting to fi...

background: the prevalence of diabetes mellitus (dm) is increasing, and thus, its mental consequences, such as depression, have an increasing trend. the goal of the present study was the determination of the prevalence of depression and some of its related factors in patients with type ii dm who referred to the diabetes center of rafsanjan, iran, in the year 2016. materials and methods: for thi...

objective:fasting plasma glucose (fpg) analysis is the most importantmethod for detection and diagnosis of diabetes mellitus. due to difficulty and problems of this method for determination of glycemia in diabetic patients, recently the use of fasting salivary glucoseas a simple and non-invasive method to evaluate fpghas came into significant considerationof specialists. the aim of this study w...

objective: diabetes mellitus type 2 is one of the most widespread chronic metabolic diseases. in most cases, this type of diabetes is associated with alterations in levels of some inflammatory cytokines and hormones. considering anti-inflammatory properties of plant extracts rich in ascorbic acid (vitamin c) and alpha-tocopherol (vitamin e), anti-diabetic properties of these two well-known anti...

type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (atd).genetic susceptibility for autoantibody formation in association with atd and type 1 diabetes mellitus has been described with varying frequencies, but there is still debate about its prevailing situation in iran.  we have therefore investigated the prevalence of anti-thyroid peroxidase (anti-tpo) and anti t...

maternal diabetes has teratogenic effects on the evolution of the fetal cardiovascular system; as a consequence, cardiovascular malformations are the most common anomalies in infants of diabetic mothers. the present study focuses on the association of all types of diabetes in mothers with the incidence of congenital cardiovascular malformations in their infants. in this retrospective case-contr...

diabetes mellitus (dm) is a chronic heterogeneous disorder and oxidative stress is a key participant in the development and progression of it and its complications. anti-oxidant status can affect vulnerability to oxidative damage, onset and progression of diabetes and diabetes complications. superoxide dismutase 2 (sod2) is one of the major antioxidant defense systems against free radicals. sod...

Context Multiple consensus statements decree that women with diabetes mellitus should have comparable birth outcomes to women without diabetes mellitus; however, there is a scarcity of contemporary population-based studies on this issue. Objective To examine temporal trends in obstetric interventions and perinatal outcomes in a population-based cohort of women with type 1, type 2, or gestatio...